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LPP2 lipid phosphate phosphatase 2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 838072, updated on 18-Sep-2024

Summary

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Official Symbol
LPP2
Official Full Name
lipid phosphate phosphatase 2
Primary source
TAIR:AT1G15080
Locus tag
AT1G15080
See related
Araport:AT1G15080
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATLPP2; ATPAP2; F9L1.2; F9L1_2; lipid phosphate phosphatase 2; LIPID PHOSPHATE PHOSPHATASE 2; PHOSPHATIDIC ACID PHOSPHATASE 2
Summary
Encodes phosphatidic acid phosphatase. Involved in ABA signaling. Functions as a negative regulator upstream of ABI4. Expressed during germination and seed development. Expressed overall in young seedlings, in roots, hypocotyls, and vascular cells of cotyledons and leaves of 10 day-old seedlings, in flower filaments and stem elongation zones. Not expressed in anthers, pollen nor petals.
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Genomic context

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See LPP2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
8
Sequence:
Chromosome: 1; NC_003070.9 (5187549..5189673)

Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Class I glutamine amidotransferase-like superfamily protein Neighboring gene ncRNA Neighboring gene indole-3-acetic acid inducible 34 Neighboring gene alpha/beta hydrolase family protein Neighboring gene tRNA-Asn Neighboring gene ncRNA Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003070.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Arabidopsis thaliana lipid phosphate phosphatase 2 is involved in abscisic acid signalling in leaves. Paradis S, et al. Plant Physiol Biochem, 2011 Mar. PMID 21277215
  2. An important role of phosphatidic acid in ABA signaling during germination in Arabidopsis thaliana. Katagiri T, et al. Plant J, 2005 Jul. PMID 15960620
  3. Lipid phosphate phosphatases in Arabidopsis. Regulation of the AtLPP1 gene in response to stress. Pierrugues O, et al. J Biol Chem, 2001 Jun 8. PMID 11278556
  4. Expression patterns of purple acid phosphatase genes in Arabidopsis organs and functional analysis of AtPAP23 predominantly transcribed in flower. Zhu H, et al. Plant Mol Biol, 2005 Nov. PMID 16244908
  5. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Taken together our observations show that AtLPP2 is a part of ABA signalling and participate to the regulation of stomatal movements.
    Title: Arabidopsis thaliana lipid phosphate phosphatase 2 is involved in abscisic acid signalling in leaves.
  2. Two AtLPP2 T-DNA insertional mutants (lpp2-1 and lpp2-2) showed hypersensitivity to ABA and significant PA accumulation during germination. [AtLPP2]
    Title: An important role of phosphatidic acid in ABA signaling during germination in Arabidopsis thaliana.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_101377.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables acid phosphatase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables phosphatidate phosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within abscisic acid-activated signaling pathway IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in phospholipid metabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
lipid phosphate phosphatase 2
NP_172961.1
  • lipid phosphate phosphatase 2 (LPP2); FUNCTIONS IN: acid phosphatase activity, phosphatidate phosphatase activity; INVOLVED IN: abscisic acid mediated signaling pathway; LOCATED IN: plasma membrane, integral to plasma membrane; EXPRESSED IN: 14 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: Phosphatidic acid phosphatase/chloroperoxidase, N-terminal (InterPro:IPR016118), Phosphatidic acid phosphatase type 2/haloperoxidase (InterPro:IPR000326); BEST Arabidopsis thaliana protein match is: lipid phosphate phosphatase 3 (TAIR:AT3G02600.5); Has 2086 Blast hits to 2081 proteins in 377 species: Archae - 13; Bacteria - 320; Metazoa - 928; Fungi - 399; Plants - 199; Viruses - 3; Other Eukaryotes - 224 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003070.9 Reference assembly

    Range
    5187549..5189673
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_101377.5 → NP_172961.1  lipid phosphate phosphatase 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_172961.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9XI60
    UniProtKB/TrEMBL
    A0A5S9UI08, A0A654EB10, A0A7G2DTU4
    Conserved Domains (1) summary
    PLN02250
    Location:1 → 290
    PLN02250; lipid phosphate phosphatase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9XI60.1

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