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Zincin-like metalloproteases family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 836688, updated on 18-Sep-2024

Summary

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Official Full Name
Zincin-like metalloproteases family protein
Primary source
TAIR:AT5G65620
Locus tag
AT5G65620
See related
Araport:AT5G65620
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
K21L13.14; K21L13_14; OOP; organellar oligopeptidase; thimet metalloendopeptidase 1; TOP1
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Genomic context

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Location:
chromosome: 5
Exon count:
17
Sequence:
Chromosome: 5; NC_003076.8 (26221829..26225903)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene tRNA-Asn Neighboring gene global transcription factor group E7 Neighboring gene ncRNA Neighboring gene beta HLH protein 93

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Organellar oligopeptidase (OOP) provides a complementary pathway for targeting peptide degradation in mitochondria and chloroplasts. Kmiec B, et al. Proc Natl Acad Sci U S A, 2013 Oct 1. PMID 24043784, Free PMC Article
  2. Proteome-Wide Analysis of Cysteine Reactivity during Effector-Triggered Immunity. McConnell EW, et al. Plant Physiol, 2019 Apr. PMID 30510037, Free PMC Article
  3. The Arabidopsis oligopeptidases TOP1 and TOP2 are salicylic acid targets that modulate SA-mediated signaling and the immune response. Moreau M, et al. Plant J, 2013 Nov. PMID 24004003
  4. The oligomeric stromal proteome of Arabidopsis thaliana chloroplasts. Peltier JB, et al. Mol Cell Proteomics, 2006 Jan. PMID 16207701
  5. Isolation and identification of ubiquitin-related proteins from Arabidopsis seedlings. Igawa T, et al. J Exp Bot, 2009. PMID 19429840, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. role in maintaining the proper level and dynamics of proteome oxidation during effector-triggered immunity
    Title: Proteome-Wide Analysis of Cysteine Reactivity during Effector-Triggered Immunity.
  2. Organellar oligopeptidase (OOP) provides a complementary pathway for targeting peptide degradation in mitochondria and chloroplasts. [Organellar oligopeptidase[ [OOP]
    Title: Organellar oligopeptidase (OOP) provides a complementary pathway for targeting peptide degradation in mitochondria and chloroplasts.
  3. Interacts with protein targets to mediate salicylic acid-dependent signaling necessary for the immune response to avirulent pathogens.
    Title: The Arabidopsis oligopeptidases TOP1 and TOP2 are salicylic acid targets that modulate SA-mediated signaling and the immune response.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_125960.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chloroplast HDA PubMed 
located_in chloroplast stroma HDA PubMed 
NOT located_in cytosol RCA
inferred from Reviewed Computational Analysis
more info
 PubMed 
located_in mitochondrion ISM
Inferred from Sequence Model
more info
  
located_in plastid HDA PubMed 

General protein information

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Preferred Names
Zincin-like metalloproteases family protein
NP_569013.1
  • Zincin-like metalloproteases family protein; FUNCTIONS IN: metalloendopeptidase activity; INVOLVED IN: proteolysis; LOCATED IN: cytosol, chloroplast, chloroplast stroma; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase M3A/M3B, thimet/oligopeptidase F (InterPro:IPR001567); BEST Arabidopsis thaliana protein match is: Zincin-like metalloproteases family protein (TAIR:AT5G10540.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    26221829..26225903
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001345702.1 → NP_001332654.1  Zincin-like metalloproteases family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1R7T3A4, A0A654GEE4
    Conserved Domains (1) summary
    cd06456
    Location:154 → 798
    M3A_DCP; Peptidase family M3, dipeptidyl carboxypeptidase (DCP)

  2. NM_125960.3 → NP_569013.1  Zincin-like metalloproteases family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_569013.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q94AM1, Q9LSL3
    UniProtKB/TrEMBL
    A0A654GEE4
    Conserved Domains (2) summary
    cd06456
    Location:140 → 784
    M3A_DCP; Peptidase family M3 dipeptidyl carboxypeptidase (DCP)
    COG0339
    Location:93 → 786
    Dcp; Zn-dependent oligopeptidase [Posttranslational modification, protein turnover, chaperones]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q94AM1.1

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