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ERL1 ERECTA-like 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 836344, updated on 18-Sep-2024

Summary

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Official Symbol
ERL1
Official Full Name
ERECTA-like 1
Primary source
TAIR:AT5G62230
Locus tag
AT5G62230
See related
Araport:AT5G62230
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ERECTA-like 1; MMI9.14; MMI9_14
Summary
Encodes a receptor-like kinase that, together with ER and ERL2 governs the initial decision of protodermal cells to either divide proliferatively to produce pavement cells or divide asymmetrically to generate stomatal complexes. It is important for maintaining stomatal stem cell activity and preventing terminal differentiation of the meristemoid into the guard mother cell. Along with erl2 functionally compensates for loss of erecta during integument development. Its transcript levels change after inducing MUTE expression in a mute background.
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Genomic context

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See ERL1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
27
Sequence:
Chromosome: 5; NC_003076.8 (24996129..25002439)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene glycosyltransferase 18 Neighboring gene ncRNA Neighboring gene Cell cycle regulated microtubule associated protein Neighboring gene microtubule-associated protein 65-9 Neighboring gene AT hook motif DNA-binding family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. ERECTA-family receptor kinase genes redundantly prevent premature progression of secondary growth in the Arabidopsis hypocotyl. Ikematsu S, et al. New Phytol, 2017 Mar. PMID 27891614
  2. ERECTA receptor-kinases play a key role in the appropriate timing of seed germination under changing salinity. Nanda AK, et al. J Exp Bot, 2019 Nov 18. PMID 31504732, Free PMC Article
  3. A receptor-like protein acts as a specificity switch for the regulation of stomatal development. Lin G, et al. Genes Dev, 2017 May 1. PMID 28536146, Free PMC Article
  4. Autocrine regulation of stomatal differentiation potential by EPF1 and ERECTA-LIKE1 ligand-receptor signaling. Qi X, et al. Elife, 2017 Mar 7. PMID 28266915, Free PMC Article
  5. Regulation of floral patterning and organ identity by Arabidopsis ERECTA-family receptor kinase genes. Bemis SM, et al. J Exp Bot, 2013 Dec. PMID 24006425

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. ERECTA receptor-kinases play a key role in the appropriate timing of seed germination under changing salinity.
    Title: ERECTA receptor-kinases play a key role in the appropriate timing of seed germination under changing salinity.
  2. ER and ERL1 redundantly prevent premature progression of sequential events in secondary growth.
    Title: ERECTA-family receptor kinase genes redundantly prevent premature progression of secondary growth in the Arabidopsis hypocotyl.
  3. Here, the authors report that EPF1 and its primary receptor ERECTA-LIKE1 (ERL1) target MUTE, a transcription factor specifying the proliferation-to-differentiation switch within the stomatal cell lineages. In turn, MUTE directly induces ERL1.
    Title: Autocrine regulation of stomatal differentiation potential by EPF1 and ERECTA-LIKE1 ligand-receptor signaling.
  4. ER-family signalling is crucial for ensuring proper expression domains of floral meristem and floral organ identity determinants, and further implies the existence of a non-canonical downstream pathway.
    Title: Regulation of floral patterning and organ identity by Arabidopsis ERECTA-family receptor kinase genes.
  5. ER, ERL1 and ERL2 proteins are essential for PIN1 expression in the forming midvein of future leaf primordia and in the vasculature of emerging leaves.
    Title: ERECTA family genes regulate auxin transport in the shoot apical meristem and forming leaf primordia.
  6. The ER family regulates stem cell homeostasis via buffering its cytokinin responsiveness in the Shoot apical meristem (SAM).
    Title: ERECTA-family receptor kinases regulate stem cell homeostasis via buffering its cytokinin responsiveness in the shoot apical meristem.
  7. Both ER/ERL1/ERL2 and MPK3/MPK6 play important roles in normal anther lobe formation and anther cell differentiation.
    Title: Regulation of Arabidopsis early anther development by the mitogen-activated protein kinases, MPK3 and MPK6, and the ERECTA and related receptor-like kinases.
  8. ERL2 is haploinsufficient for maintaining female fertility in the absence of ER and ERL1.
    Title: Haploinsufficiency after successive loss of signaling reveals a role for ERECTA-family genes in Arabidopsis ovule development.
  9. Three ERECTA-family leucine-rich repeat-receptor-like kinases (ER, ERL1,ERL2) together control stomatal patterning, with specific family members regulating specification of stomatal stem cell fate & differentiation of guard cells. [ERL1]
    Title: Stomatal patterning and differentiation by synergistic interactions of receptor kinases.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001203666.1
NM_125617.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables receptor serine/threonine kinase binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables signaling receptor binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within embryo sac development IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within plant ovule development IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within stomatal complex morphogenesis IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
ERECTA-like 1
NP_001190595.1
  • ERECTA-like 1 (ERL1); FUNCTIONS IN: kinase activity; INVOLVED IN: stomatal complex morphogenesis, embryo sac development, ovule development; LOCATED IN: endomembrane system; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), Leucine-rich repeat-containing N-terminal domain, type 2 (InterPro:IPR013210), Leucine-rich repeat (InterPro:IPR001611), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase, catalytic domain (InterPro:IPR000719), Leucine-rich repeat, typical subtype (InterPro:IPR003591), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635); BEST Arabidopsis thaliana protein match is: ERECTA-like 2 (TAIR:AT5G07180.1).
NP_201029.1
  • ERECTA-like 1 (ERL1); FUNCTIONS IN: kinase activity; INVOLVED IN: stomatal complex morphogenesis, embryo sac development, ovule development; LOCATED IN: endomembrane system; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Leucine-rich repeat-containing N-terminal domain, type 2 (InterPro:IPR013210), Leucine-rich repeat (InterPro:IPR001611), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: ERECTA-like 2 (TAIR:AT5G07180.1); Has 222426 Blast hits to 137934 proteins in 3754 species: Archae - 152; Bacteria - 22676; Metazoa - 73214; Fungi - 10790; Plants - 88135; Viruses - 480; Other Eukaryotes - 26979 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    24996129..25002439
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001203666.1 → NP_001190595.1  ERECTA-like 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001190595.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178UB72, F4K6F3
    Conserved Domains (5) summary
    PLN00113
    Location:12 → 868
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    cd00116
    Location:120 → 215
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    sd00033
    Location:97 → 120
    LRR_RI; leucine-rich repeat [structural motif]
    pfam08263
    Location:27 → 67
    LRRNT_2; Leucine rich repeat N-terminal domain
    cl21453
    Location:606 → 866
    PKc_like; Protein Kinases, catalytic domain

  2. NM_125617.3 → NP_201029.1  ERECTA-like 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_201029.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    C0LGW6, Q6XAT3, Q8GXT4, Q9LVB3
    UniProtKB/TrEMBL
    A0A178UB72, A0A5S9YGT9, A0A654GDB1
    Conserved Domains (2) summary
    PLN00113
    Location:12 → 916
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00033
    Location:266 → 287
    LRR_RI; leucine-rich repeat [structural motif]
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
C0LGW6.1

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