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LAC8 laccase 8 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 831877, updated on 18-Sep-2024

Summary

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Official Symbol
LAC8
Official Full Name
laccase 8
Primary source
TAIR:AT5G01040
Locus tag
AT5G01040
See related
Araport:AT5G01040
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F7J8.20; F7J8_20; laccase 8
Summary
putative laccase, knockout mutant showed early flowering
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Genomic context

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See LAC8 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
6
Sequence:
Chromosome: 5; NC_003076.8 (13128..16236, complement)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Protein kinase superfamily protein Neighboring gene enolase, putative (DUF3527) Neighboring gene Laccase/Diphenol oxidase family protein Neighboring gene kinase with tetratricopeptide repeat domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Mutant identification and characterization of the laccase gene family in Arabidopsis. Cai X, et al. J Exp Bot, 2006. PMID 16804053
  2. MicroRNA-mediated systemic down-regulation of copper protein expression in response to low copper availability in Arabidopsis. Abdel-Ghany SE, et al. J Biol Chem, 2008 Jun 6. PMID 18408011, Free PMC Article
  3. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

GeneRIFs: Gene References Into Functions

General gene information

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NM_120181.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables copper ion binding IEA
Inferred from Electronic Annotation
more info
  
enables hydroquinone:oxygen oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within response to copper ion IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within vegetative to reproductive phase transition of meristem IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
laccase 8
NP_195724.1
  • laccase 8 (LAC8); FUNCTIONS IN: laccase activity; INVOLVED IN: vegetative to reproductive phase transition of meristem, response to copper ion; LOCATED IN: endomembrane system, apoplast; EXPRESSED IN: fruit, root, flower; CONTAINS InterPro DOMAIN/s: Multicopper oxidase, type 2 (InterPro:IPR011706), Multicopper oxidase, type 3 (InterPro:IPR011707), Laccase (InterPro:IPR017761), Cupredoxin (InterPro:IPR008972), Multicopper oxidase, type 1 (InterPro:IPR001117); BEST Arabidopsis thaliana protein match is: Laccase/Diphenol oxidase family protein (TAIR:AT5G01050.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    13128..16236 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_120181.5 → NP_195724.1  laccase 8 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_195724.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q67YL1, Q8GYV9, Q9LFD2
    UniProtKB/TrEMBL
    A0A5S9Y161, A0A654FX64
    Conserved Domains (4) summary
    cd13849
    Location:30 → 146
    CuRO_1_LCC_plant; The first cupredoxin domain of plant laccases
    cd13875
    Location:161 → 303
    CuRO_2_LCC_plant; The second cupredoxin domain of the plant laccases
    cd13897
    Location:406 → 549
    CuRO_3_LCC_plant; The third cupredoxin domain of the plant laccases
    TIGR03389
    Location:25 → 566
    laccase; laccase, plant
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LFD2.1

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