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Zincin-like metalloproteases family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 830919, updated on 18-Sep-2024

Summary

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Official Full Name
Zincin-like metalloproteases family protein
Primary source
TAIR:AT5G10540
Locus tag
AT5G10540
See related
Araport:AT5G10540
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F12B17.110; F12B17_110; thimet metalloendopeptidase 2; TOP2
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Genomic context

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Location:
chromosome: 5
Exon count:
18
Sequence:
Chromosome: 5; NC_003076.8 (3324812..3334971)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene AINTEGUMENTA-like 6 Neighboring gene ROP binding protein kinases 1 Neighboring gene tRNA-Arg Neighboring gene Concanavalin A-like lectin protein kinase family protein Neighboring gene ncRNA Neighboring gene global transcription factor group E2 Neighboring gene miscRNA Neighboring gene Glycosyl hydrolase family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Proteome-Wide Analysis of Cysteine Reactivity during Effector-Triggered Immunity. McConnell EW, et al. Plant Physiol, 2019 Apr. PMID 30510037, Free PMC Article
  2. The Arabidopsis oligopeptidases TOP1 and TOP2 are salicylic acid targets that modulate SA-mediated signaling and the immune response. Moreau M, et al. Plant J, 2013 Nov. PMID 24004003
  3. Hydroponic isotope labelling of entire plants (HILEP) for quantitative plant proteomics; an oxidative stress case study. Bindschedler LV, et al. Phytochemistry, 2008 Jul. PMID 18538804
  4. Isolation and identification of ubiquitin-related proteins from Arabidopsis seedlings. Igawa T, et al. J Exp Bot, 2009. PMID 19429840, Free PMC Article
  5. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. role in maintaining the proper level and dynamics of proteome oxidation during effector-triggered immunity
    Title: Proteome-Wide Analysis of Cysteine Reactivity during Effector-Triggered Immunity.
  2. Interacts with protein targets to mediate salicylic acid (SA)-dependent signaling necessary for the immune response to avirulent pathogens.
    Title: The Arabidopsis oligopeptidases TOP1 and TOP2 are salicylic acid targets that modulate SA-mediated signaling and the immune response.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_121092.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in apoplast HDA PubMed 
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in cytosol HDA PubMed 
located_in plasma membrane HDA PubMed 

General protein information

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Preferred Names
Zincin-like metalloproteases family protein
NP_568232.1
  • Zincin-like metalloproteases family protein; FUNCTIONS IN: metalloendopeptidase activity; INVOLVED IN: response to cadmium ion, proteolysis; LOCATED IN: cytosol, apoplast, chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase M3A/M3B, thimet/oligopeptidase F (InterPro:IPR001567); BEST Arabidopsis thaliana protein match is: Zincin-like metalloproteases family protein (TAIR:AT5G65620.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    3324812..3334971
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_121092.4 → NP_568232.1  Zincin-like metalloproteases family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_568232.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q949P2, Q9LXA6
    UniProtKB/TrEMBL
    A0A178UD97, A0A5S9Y587
    Conserved Domains (1) summary
    cd06456
    Location:28 → 696
    M3A_DCP; Peptidase family M3, dipeptidyl carboxypeptidase (DCP)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q949P2.1

Gene LinkOut

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