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ABI1 Protein phosphatase 2C family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 828714, updated on 18-Sep-2024

Summary

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Official Symbol
ABI1
Official Full Name
Protein phosphatase 2C family protein
Primary source
TAIR:AT4G26080
Locus tag
AT4G26080
See related
Araport:AT4G26080
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ABA INSENSITIVE 1; AtABI1; F20B18.190; F20B18_190; PROTEIN PHOSPHATASE 2C ABI1
Summary
Involved in abscisic acid (ABA) signal transduction. Negative regulator of ABA promotion of stomatal closure.
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Genomic context

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See ABI1 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
4
Sequence:
Chromosome: 4; NC_003075.7 (13219915..13222376, complement)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Ribosomal protein L18ae family Neighboring gene MAP kinase/ ERK kinase 1 Neighboring gene ncRNA Neighboring gene NB-ARC domain-containing disease resistance protein Neighboring gene casein kinase 1 Neighboring gene nucleosome assembly protein1;1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The UBC27-AIRP3 ubiquitination complex modulates ABA signaling by promoting the degradation of ABI1 in Arabidopsis. Pan W, et al. Proc Natl Acad Sci U S A, 2020 Nov 3. PMID 33077597, Free PMC Article
  2. ABI1 regulates carbon/nitrogen-nutrient signal transduction independent of ABA biosynthesis and canonical ABA signalling pathways in Arabidopsis. Lu Y, et al. J Exp Bot, 2015 May. PMID 25795738, Free PMC Article
  3. Endodermal ABA signaling promotes lateral root quiescence during salt stress in Arabidopsis seedlings. Duan L, et al. Plant Cell, 2013 Jan. PMID 23341337, Free PMC Article
  4. Expression of the Arabidopsis mutant ABI1 gene alters abscisic acid sensitivity, stomatal development, and growth morphology in gray poplars. Arend M, et al. Plant Physiol, 2009 Dec. PMID 19837818, Free PMC Article
  5. Gene expression profiling of ozone-treated Arabidopsis abi1td insertional mutant: protein phosphatase 2C ABI1 modulates biosynthesis ratio of ABA and ethylene. Ludwików A, et al. Planta, 2009 Oct. PMID 19705149

See all (83) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. TMK1-based auxin signaling regulates abscisic acid responses via phosphorylating ABI1/2 in Arabidopsis.
    Title: TMK1-based auxin signaling regulates abscisic acid responses via phosphorylating ABI1/2 in Arabidopsis.
  2. Protein Phosphatases Type 2C Group A Interact with and Regulate the Stability of ACC Synthase 7 in Arabidopsis.
    Title: Protein Phosphatases Type 2C Group A Interact with and Regulate the Stability of ACC Synthase 7 in Arabidopsis.
  3. The UBC27-AIRP3 ubiquitination complex modulates ABA signaling by promoting the degradation of ABI1 in Arabidopsis.
    Title: The UBC27-AIRP3 ubiquitination complex modulates ABA signaling by promoting the degradation of ABI1 in Arabidopsis.
  4. ABA signaling is negatively regulated by GbWRKY1 through JAZ1 and ABI1 to affect salt and drought tolerance.
    Title: ABA signaling is negatively regulated by GbWRKY1 through JAZ1 and ABI1 to affect salt and drought tolerance.
  5. ABI1, ABI2, and HAI1 promoters of PP2C are regulated by repressors; BRM ATPase contributes to the repression of PP2C gene transcription
    Title: Chromatin remodeling for the transcription of type 2C protein phosphatase genes in response to salt stress.
  6. ABI1 is involved in auxin-triggered lateral root development.ABI1 regulates HSP22 expression.
    Title: The sHSP22 Heat Shock Protein Requires the ABI1 Protein Phosphatase to Modulate Polar Auxin Transport and Downstream Responses.
  7. Data indicate that bscisic acid (ABA) signaling is repressed by group A type 2C protein phosphatases (PP2Cs), and then ABA binds to its receptor of the ACTIN RESISTANCE1 (PYR1), PYR1-LIKE (PYL), and REGULATORY COMPONENTS OF ABA RECEPTORS (RCAR) family, which, in turn, inhibits PP2Cs and activates downstream ABA signaling.
    Title: A Novel Chemical Inhibitor of ABA Signaling Targets All ABA Receptors.
  8. Phosphatase ABI1 and okadaic acid-sensitive phosphatases of the PPP family are negative regulators of salt stress-activated SnRK2.4.
    Title: Phosphatase ABI1 and okadaic acid-sensitive phosphoprotein phosphatases inhibit salt stress-activated SnRK2.4 kinase.
  9. ABI1 acts to inhibit MAPKKK18 kinase activity, but also affects MAPKKK18 protein turnover via the ubiquitin-proteasome pathway. SnRK2.6 kinase also seems to be important for the regulation of MAPKKK18 function.
    Title: Regulation of Arabidopsis MAPKKK18 by ABI1 and SnRK2, components of the ABA signaling pathway.
  10. ABI1 regulates the activity and promotes proteasomal degradation of MKKK18.
    Title: Arabidopsis ABA-Activated Kinase MAPKKK18 is Regulated by Protein Phosphatase 2C ABI1 and the Ubiquitin-Proteasome Pathway.
Submit: New GeneRIF Correction See all GeneRIFs (30)

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_118741.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables calcium ion binding TAS
Traceable Author Statement
more info
 PubMed 
enables kinase binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables myosin phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables phosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables phosphoprotein phosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein kinase binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein serine/threonine phosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of abscisic acid-activated signaling pathway IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within negative regulation of abscisic acid-activated signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of abscisic acid-activated signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within protein dephosphorylation IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in protein dephosphorylation IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within protein dephosphorylation TAS
Traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within regulation of abscisic acid-activated signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within regulation of stomatal movement IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in response to abscisic acid IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within response to abscisic acid IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to cold IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to heat IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
part_of protein serine/threonine phosphatase complex TAS
Traceable Author Statement
more info
 PubMed 

General protein information

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Preferred Names
Protein phosphatase 2C family protein
NP_194338.1
  • ABA INSENSITIVE 1 (ABI1); CONTAINS InterPro DOMAIN/s: Protein phosphatase 2C, manganese/magnesium aspartate binding site (InterPro:IPR000222), Protein phosphatase 2C-related (InterPro:IPR001932), Protein phosphatase 2C (InterPro:IPR015655), Protein phosphatase 2C, N-terminal (InterPro:IPR014045); BEST Arabidopsis thaliana protein match is: Protein phosphatase 2C family protein (TAIR:AT5G57050.1); Has 6864 Blast hits to 6731 proteins in 444 species: Archae - 4; Bacteria - 295; Metazoa - 1756; Fungi - 772; Plants - 2717; Viruses - 7; Other Eukaryotes - 1313 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    13219915..13222376 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_118741.3 → NP_194338.1  Protein phosphatase 2C family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_194338.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P49597, Q0WW30, Q43717, Q94C87
    UniProtKB/TrEMBL
    A0A178V1P9, A0A5S9XWB7
    Conserved Domains (1) summary
    smart00332
    Location:119 → 420
    PP2Cc; Serine/threonine phosphatases, family 2C, catalytic domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P49597.2

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