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[ Arabidopsis thaliana (thale cress) ]

Gene ID: 828301, updated on 22-Aug-2024

Summary

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Primary source
Araport:AT4G22120
Locus tag
AT4G22120
See related
TAIR:AT4G22120
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F1N20.220; F1N20_220
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Genomic context

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Location:
chromosome: 4
Exon count:
10
Sequence:
Chromosome: 4; NC_003075.7 (11715607..11719873, complement)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene GroES-like zinc-binding dehydrogenase family protein Neighboring gene SCR-like 14 Neighboring gene STRUBBELIG-receptor family 8 Neighboring gene PHD finger family protein / bromo-adjacent homology (BAH) domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structure of the hyperosmolality-gated calcium-permeable channel OSCA1.2. Liu X, et al. Nat Commun, 2018 Nov 29. PMID 30498218, Free PMC Article
  2. DUF221 proteins are a family of osmosensitive calcium-permeable cation channels conserved across eukaryotes. Hou C, et al. Cell Res, 2014 May. PMID 24503647, Free PMC Article
  3. OSCA/TMEM63 are an Evolutionarily Conserved Family of Mechanically Activated Ion Channels. Murthy SE, et al. Elife, 2018 Nov 1. PMID 30382938, Free PMC Article
  4. Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry. Nühse TS, et al. Mol Cell Proteomics, 2003 Nov. PMID 14506206
  5. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

GeneRIFs: Gene References Into Functions

General gene information

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Homology

NM_001084956.2
NM_001125555.2
NM_001125556.2
NM_001125557.1
NM_001203867.2
NM_118333.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables calcium-activated cation channel activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables mechanosensitive monoatomic ion channel activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in monoatomic cation transport IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane HDA PubMed 
located_in plasma membrane ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
ERD (early-responsive to dehydration stress) family protein
NP_001078425.1
  • ERD (early-responsive to dehydration stress) family protein; LOCATED IN: plasma membrane; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF221 (InterPro:IPR003864); BEST Arabidopsis thaliana protein match is: ERD (early-responsive to dehydration stress) family protein (TAIR:AT4G04340.1); Has 1475 Blast hits to 1296 proteins in 202 species: Archae - 0; Bacteria - 0; Metazoa - 185; Fungi - 716; Plants - 435; Viruses - 0; Other Eukaryotes - 139 (source: NCBI BLink).
NP_001119027.1
  • ERD (early-responsive to dehydration stress) family protein; LOCATED IN: plasma membrane; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF221 (InterPro:IPR003864); BEST Arabidopsis thaliana protein match is: ERD (early-responsive to dehydration stress) family protein (TAIR:AT4G04340.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
NP_001119028.1
  • ERD (early-responsive to dehydration stress) family protein; LOCATED IN: plasma membrane; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF221 (InterPro:IPR003864); BEST Arabidopsis thaliana protein match is: ERD (early-responsive to dehydration stress) family protein (TAIR:AT4G04340.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
NP_001119029.1
  • ERD (early-responsive to dehydration stress) family protein; LOCATED IN: plasma membrane; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF221 (InterPro:IPR003864); BEST Arabidopsis thaliana protein match is: ERD (early-responsive to dehydration stress) family protein (TAIR:AT4G04340.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
NP_001190796.1
  • ERD (early-responsive to dehydration stress) family protein; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF221 (InterPro:IPR003864); BEST Arabidopsis thaliana protein match is: ERD (early-responsive to dehydration stress) family protein (TAIR:AT4G04340.1).
NP_193943.2
  • ERD (early-responsive to dehydration stress) family protein; LOCATED IN: plasma membrane; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF221 (InterPro:IPR003864); BEST Arabidopsis thaliana protein match is: ERD (early-responsive to dehydration stress) family protein (TAIR:AT4G04340.1); Has 1475 Blast hits to 1296 proteins in 202 species: Archae - 0; Bacteria - 0; Metazoa - 185; Fungi - 716; Plants - 435; Viruses - 0; Other Eukaryotes - 139 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    11715607..11719873 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_118333.5 → NP_193943.2  ERD (early-responsive to dehydration stress) family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_193943.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A0A097NUP4, O65460, Q56YV1, Q5XEZ5
    UniProtKB/TrEMBL
    A0A178UVB9, A0A5S9XV59, A0A654FRM3
    Conserved Domains (2) summary
    COG5594
    Location:3 → 680
    COG5594; Uncharacterized integral membrane protein [Function unknown]
    pfam02714
    Location:374 → 645
    RSN1_7TM; Calcium-dependent channel, 7TM region, putative phosphate

  2. NM_001203867.2 → NP_001190796.1  ERD (early-responsive to dehydration stress) family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001190796.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A0A097NUP4, O65460, Q56YV1, Q5XEZ5
    UniProtKB/TrEMBL
    A0A178UVB9, A0A5S9XV59, A0A654FRM3
    Conserved Domains (2) summary
    COG5594
    Location:3 → 680
    COG5594; Uncharacterized integral membrane protein [Function unknown]
    pfam02714
    Location:374 → 645
    RSN1_7TM; Calcium-dependent channel, 7TM region, putative phosphate

  3. NM_001084956.2 → NP_001078425.1  ERD (early-responsive to dehydration stress) family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001078425.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A0A097NUP4, O65460, Q56YV1, Q5XEZ5
    UniProtKB/TrEMBL
    A0A178UVB9, A0A5S9XV59, A0A654FRM3
    Conserved Domains (2) summary
    COG5594
    Location:3 → 680
    COG5594; Uncharacterized integral membrane protein [Function unknown]
    pfam02714
    Location:374 → 645
    RSN1_7TM; Calcium-dependent channel, 7TM region, putative phosphate

  4. NM_001125555.2 → NP_001119027.1  ERD (early-responsive to dehydration stress) family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001119027.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A0A097NUP4, O65460, Q56YV1, Q5XEZ5
    UniProtKB/TrEMBL
    A0A178UVB9, A0A5S9XV59, A0A654FRM3
    Conserved Domains (2) summary
    COG5594
    Location:3 → 680
    COG5594; Uncharacterized integral membrane protein [Function unknown]
    pfam02714
    Location:374 → 645
    RSN1_7TM; Calcium-dependent channel, 7TM region, putative phosphate

  5. NM_001125556.2 → NP_001119028.1  ERD (early-responsive to dehydration stress) family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001119028.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A0A097NUP4, O65460, Q56YV1, Q5XEZ5
    UniProtKB/TrEMBL
    A0A178UVB9, A0A5S9XV59, A0A654FRM3
    Conserved Domains (2) summary
    COG5594
    Location:3 → 680
    COG5594; Uncharacterized integral membrane protein [Function unknown]
    pfam02714
    Location:374 → 645
    RSN1_7TM; Calcium-dependent channel, 7TM region, putative phosphate

  6. NM_001125557.1 → NP_001119029.1  ERD (early-responsive to dehydration stress) family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001119029.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A0A097NUP4, O65460, Q56YV1, Q5XEZ5
    UniProtKB/TrEMBL
    A0A178UVB9, A0A5S9XV59, A0A654FRM3
    Conserved Domains (2) summary
    COG5594
    Location:3 → 680
    COG5594; Uncharacterized integral membrane protein [Function unknown]
    pfam02714
    Location:374 → 645
    RSN1_7TM; Calcium-dependent channel, 7TM region, putative phosphate
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5XEZ5.1

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