GPAT8 glycerol-3-phosphate acyltransferase 8 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: GPAT8
Official Full Name: glycerol-3-phosphate acyltransferase 8
Primary source: TAIR:AT4G00400
Locus tag: AT4G00400
See related: Araport:AT4G00400
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: AtGPAT8; A_IG005I10.4; A_IG005I10_4; F5I10.4; F5I10_4; glycerol-3-phosphate acyltransferase 8; GLYCEROL-3-PHOSPHATE sn-2-ACYLTRANSFERASE 8
Summary: bifunctional sn-glycerol-3-phosphate 2-O-acyltransferase/phosphatase. Involved in cutin assembly and is functionally redundant with GPAT4.
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Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

Function identification of Arabidopsis GPAT4 and GPAT8 in the biosynthesis of suberin and cuticular wax.
Title: Function identification of Arabidopsis GPAT4 and GPAT8 in the biosynthesis of suberin and cuticular wax.
Data indicated that both GPAT8 and GPAT9 were localized to the endoplasmic reticulum and their N- and C-termini were oriented towards the cytosol.
Title: Arabidopsis thaliana GPAT8 and GPAT9 are localized to the ER and possess distinct ER retrieval signals: functional divergence of the dilysine ER retrieval motif in plant cells.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_116264.6

Function	Evidence Code	Pubs
enables glycerol-3-phosphate 2-O-acyltransferase activity	IDA Inferred from Direct Assay more info	PubMed
enables glycerol-3-phosphate O-acyltransferase activity	IEA Inferred from Electronic Annotation more info
enables phosphatase activity	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
involved_in CDP-diacylglycerol biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within cutin biosynthetic process	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	IDA Inferred from Direct Assay more info	PubMed

NP_191950.2

glycerol-3-phosphate acyltransferase 8 (GPAT8); FUNCTIONS IN: glycerol-3-phosphate O-acyltransferase activity, acyltransferase activity; INVOLVED IN: metabolic process, cutin biosynthetic process; LOCATED IN: endoplasmic reticulum; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Phospholipid/glycerol acyltransferase (InterPro:IPR002123); BEST Arabidopsis thaliana protein match is: glycerol-3-phosphate acyltransferase 4 (TAIR:AT1G01610.1); Has 380 Blast hits to 369 proteins in 27 species: Archae - 0; Bacteria - 6; Metazoa - 8; Fungi - 0; Plants - 360; Viruses - 0; Other Eukaryotes - 6 (source: NCBI BLink).