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NCED4 nine-cis-epoxycarotenoid dioxygenase 4 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 827655, updated on 18-Sep-2024

Summary

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Official Symbol
NCED4
Official Full Name
nine-cis-epoxycarotenoid dioxygenase 4
Primary source
TAIR:AT4G19170
Locus tag
AT4G19170
See related
Araport:AT4G19170
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
carotenoid cleavage dioxygenase 4; CCD4; nine-cis-epoxycarotenoid dioxygenase 4; T18B16.140; T18B16_140
Summary
chloroplast-targeted member of a family of enzymes similar to nine-cis-epoxycarotenoid dioxygenase
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Genomic context

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See NCED4 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
1
Sequence:
Chromosome: 4; NC_003075.7 (10481619..10483879)

Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Ankyrin repeat family protein Neighboring gene ncRNA Neighboring gene transglutaminase family protein Neighboring gene GDA1/CD39 nucleoside phosphatase family protein Neighboring gene nodulin MtN21 /EamA-like transporter family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Carotenoid cleavage dioxygenase4 is a negative regulator of β-carotene content in Arabidopsis seeds. Gonzalez-Jorge S, et al. Plant Cell, 2013 Dec. PMID 24368792, Free PMC Article
  2. Enzymatic study on AtCCD4 and AtCCD7 and their potential to form acyclic regulatory metabolites. Bruno M, et al. J Exp Bot, 2016 Nov. PMID 27811075, Free PMC Article
  3. Arabidopsis VARIEGATED 3 encodes a chloroplast-targeted, zinc-finger protein required for chloroplast and palisade cell development. Naested H, et al. J Cell Sci, 2004 Sep 15. PMID 15340011
  4. Phosphoproteome analyses pinpoint the F-box protein SLOW MOTION as a regulator of warm temperature-mediated hypocotyl growth in Arabidopsis. Zhu S, et al. New Phytol, 2024 Jan. PMID 37950543,
  5. The Plastoglobule-Localized Metallopeptidase PGM48 Is a Positive Regulator of Senescence in Arabidopsis thaliana. Bhuiyan NH, et al. Plant Cell, 2016 Dec. PMID 27895226, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. enzymatic potential to form acyclic regulatory metabolites
    Title: Enzymatic study on AtCCD4 and AtCCD7 and their potential to form acyclic regulatory metabolites.
  2. CCD4 plays a major role in beta-carotene degradation in drying seeds and senescing leaves
    Title: Carotenoid cleavage dioxygenase4 is a negative regulator of β-carotene content in Arabidopsis seeds.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_118036.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in beta-carotene catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast HDA PubMed 
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in cytosol HDA PubMed 
located_in plastoglobule HDA PubMed 

General protein information

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Preferred Names
nine-cis-epoxycarotenoid dioxygenase 4
NP_193652.1
  • nine-cis-epoxycarotenoid dioxygenase 4 (NCED4); LOCATED IN: chloroplast, plastoglobule; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Carotenoid oxygenase (InterPro:IPR004294); BEST Arabidopsis thaliana protein match is: nine-cis-epoxycarotenoid dioxygenase 5 (TAIR:AT1G30100.1); Has 2918 Blast hits to 2864 proteins in 491 species: Archae - 16; Bacteria - 796; Metazoa - 323; Fungi - 173; Plants - 887; Viruses - 0; Other Eukaryotes - 723 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003075.7 Reference assembly

    Range
    10481619..10483879
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_118036.3 → NP_193652.1  nine-cis-epoxycarotenoid dioxygenase 4 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_193652.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O49675
    UniProtKB/TrEMBL
    A0A7G2EYQ3
    Conserved Domains (1) summary
    cl10080
    Location:17 → 594
    RPE65; Retinal pigment epithelial membrane protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O49675.1

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