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DHDPS1 dihydrodipicolinate synthase 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 825259, updated on 18-Sep-2024

Summary

Official Symbol
DHDPS1
Official Full Name
dihydrodipicolinate synthase 1
Primary source
TAIR:AT3G60880
Locus tag
AT3G60880
See related
Araport:AT3G60880
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
DHDPS; DIHYDRODIPICOLINATE SYNTHASE; dihydrodipicolinate synthase 1
Summary
Encodes a dihydropicolinate synthase involved in lysine biosynthesis. The enzyme is allosterically inhibited by lysine. It is predicted to localize to the cholorplast.
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Genomic context

See DHDPS1 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
3
Sequence:
Chromosome: 3; NC_003074.8 (22494739..22496697)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene SEC7-like guanine nucleotide exchange family protein Neighboring gene AT-hook motif nuclear-localized protein 18 Neighboring gene binding protein Neighboring gene FASCICLIN-like arabinogalactan-protein 10

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

NM_115952.2
NM_180399.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables 4-hydroxy-tetrahydrodipicolinate synthase activity IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
involved_in lysine biosynthetic process via diaminopimelate IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
 

General protein information

Preferred Names
dihydrodipicolinate synthase 1
NP_191647.1
  • dihydrodipicolinate synthase 1 (DHDPS1); FUNCTIONS IN: dihydrodipicolinate synthase activity; INVOLVED IN: lysine biosynthetic process via diaminopimelate, metabolic process, diaminopimelate biosynthetic process; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aldolase-type TIM barrel (InterPro:IPR013785), Dihydrodipicolinate synthase subfamily (InterPro:IPR005263), Dihydrodipicolinate synthetase (InterPro:IPR002220), Dihydrodipicolinate synthetase, active site (InterPro:IPR020625), Dihydrodipicolinate synthetase, conserved site (InterPro:IPR020624); BEST Arabidopsis thaliana protein match is: dihydrodipicolinate synthase (TAIR:AT2G45440.1); Has 13092 Blast hits to 13092 proteins in 2641 species: Archae - 342; Bacteria - 9390; Metazoa - 97; Fungi - 273; Plants - 96; Viruses - 0; Other Eukaryotes - 2894 (source: NCBI BLink).
NP_850730.1
  • dihydrodipicolinate synthase 1 (DHDPS1); FUNCTIONS IN: dihydrodipicolinate synthase activity; INVOLVED IN: lysine biosynthetic process via diaminopimelate, diaminopimelate biosynthetic process, metabolic process; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aldolase-type TIM barrel (InterPro:IPR013785), Dihydrodipicolinate synthase subfamily (InterPro:IPR005263), Dihydrodipicolinate synthetase (InterPro:IPR002220), Dihydrodipicolinate synthetase, active site (InterPro:IPR020625), Dihydrodipicolinate synthetase, conserved site (InterPro:IPR020624); BEST Arabidopsis thaliana protein match is: dihydrodipicolinate synthase (TAIR:AT2G45440.1); Has 13228 Blast hits to 13228 proteins in 2671 species: Archae - 342; Bacteria - 9527; Metazoa - 96; Fungi - 273; Plants - 96; Viruses - 0; Other Eukaryotes - 2894 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    22494739..22496697
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_180399.3NP_850730.1  dihydrodipicolinate synthase 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_850730.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O49355, Q8VZQ1, Q9LZX6, Q9SW58
    UniProtKB/TrEMBL
    A0A178V8R0, A0A5S9XMV8, A0A654FJL5
    Conserved Domains (1) summary
    PLN02417
    Location:64343
    PLN02417; dihydrodipicolinate synthase
  2. NM_115952.2NP_191647.1  dihydrodipicolinate synthase 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_191647.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178V8R0, A0A5S9XMV8
    Conserved Domains (1) summary
    PLN02417
    Location:63342
    PLN02417; dihydrodipicolinate synthase