TSA1 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: TSA1
Primary source: Araport:AT3G54640
Locus tag: AT3G54640
See related: TAIR:AT3G54640
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: TRP3; tryptophan synthase alpha chain; TRYPTOPHAN SYNTHASE ALPHA CHAIN; TRYPTOPHAN-REQUIRING 3
Summary: Catalyzes the conversion of indole-3-glycerolphosphate to indole, the penultimate reaction in the biosynthesis of tryptophan. Functions as a heterocomplex with tryptophan synthase beta subunit (TSA2).
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Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

NAI2 and TSA1 Drive Differentiation of Constitutive and Inducible ER Body Formation in Brassicaceae.
Title: NAI2 and TSA1 Drive Differentiation of Constitutive and Inducible ER Body Formation in Brassicaceae.

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NM_115321.4

Function	Evidence Code	Pubs
enables indole-3-glycerol-phosphate lyase activity	IEA Inferred from Electronic Annotation more info
enables tryptophan synthase activity	IDA Inferred from Direct Assay more info	PubMed
enables tryptophan synthase activity	IGI Inferred from Genetic Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within defense response by callose deposition in cell wall	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within defense response to bacterium	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in gravitropism	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in tryptophan biosynthetic process	IDA Inferred from Direct Assay more info	PubMed
involved_in tryptophan biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within tryptophan biosynthetic process	TAS Traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
located_in chloroplast	HDA more info	PubMed
located_in chloroplast	IDA Inferred from Direct Assay more info	PubMed
located_in chloroplast	ISM Inferred from Sequence Model more info
located_in chloroplast stroma	HDA more info	PubMed

NP_567004.1

tryptophan synthase alpha chain (TSA1); FUNCTIONS IN: tryptophan synthase activity; INVOLVED IN: tryptophan biosynthetic process, defense response to bacterium, defense response by callose deposition in cell wall; LOCATED IN: chloroplast, chloroplast stroma; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Tryptophan synthase, alpha chain, active site (InterPro:IPR018204), Aldolase-type TIM barrel (InterPro:IPR013785), Ribulose-phosphate binding barrel (InterPro:IPR011060), Tryptophan synthase, alpha chain (InterPro:IPR002028); BEST Arabidopsis thaliana protein match is: Aldolase-type TIM barrel family protein (TAIR:AT4G02610.1); Has 7625 Blast hits to 7625 proteins in 2261 species: Archae - 218; Bacteria - 4541; Metazoa - 6; Fungi - 175; Plants - 137; Viruses - 0; Other Eukaryotes - 2548 (source: NCBI BLink).