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UEV1D-4 ubiquitin E2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 824422, updated on 18-Sep-2024

Summary

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Official Symbol
UEV1D-4
Official Full Name
ubiquitin E2
Primary source
TAIR:AT3G52560
Locus tag
AT3G52560
See related
Araport:AT3G52560
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F3C22.2; MMS2 ZWEI HOMOLOGUE 4; MMZ4; UBIQUITIN E2 VARIANT 1D; ubiquitin E2 variant 1D-4; UEV1D
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Genomic context

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See UEV1D-4 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
4
Sequence:
Chromosome: 3; NC_003074.8 (19494369..19496147, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ovate family protein 18 Neighboring gene transcription repressor OFP15-like protein Neighboring gene uncharacterized protein Neighboring gene tRNA-Leu

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Arabidopsis UEV1D promotes Lysine-63-linked polyubiquitination and is involved in DNA damage response. Wen R, et al. Plant Cell, 2008 Jan. PMID 18178771, Free PMC Article
  2. Targeted interactomics reveals a complex core cell cycle machinery in Arabidopsis thaliana. Van Leene J, et al. Mol Syst Biol, 2010 Aug 10. PMID 20706207, Free PMC Article
  3. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article
  4. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
  5. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. UEV1D appears to express at a much higher level in germinating seeds and in pollen.
    Title: Arabidopsis UEV1D promotes Lysine-63-linked polyubiquitination and is involved in DNA damage response.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001084803.1
NM_001203144.1
NM_180353.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within DNA damage response IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within positive regulation of protein polyubiquitination IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within postreplication repair IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
part_of UBC13-MMS2 complex IPI
Inferred from Physical Interaction
more info
 PubMed 
located_in cytosol HDA PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
ubiquitin E2
NP_001078272.1
  • ubiquitin E2 variant 1D-4 (UEV1D-4); CONTAINS InterPro DOMAIN/s: Ubiquitin-conjugating enzyme/RWD-like (InterPro:IPR016135), Ubiquitin-conjugating enzyme, E2 (InterPro:IPR000608); BEST Arabidopsis thaliana protein match is: MMS ZWEI homologue 3 (TAIR:AT2G36060.2); Has 1152 Blast hits to 1152 proteins in 227 species: Archae - 0; Bacteria - 0; Metazoa - 609; Fungi - 146; Plants - 247; Viruses - 0; Other Eukaryotes - 150 (source: NCBI BLink).
NP_001190073.1
  • ubiquitin E2 variant 1D-4 (UEV1D-4); CONTAINS InterPro DOMAIN/s: Ubiquitin-conjugating enzyme/RWD-like (InterPro:IPR016135), Ubiquitin-conjugating enzyme, E2 (InterPro:IPR000608); BEST Arabidopsis thaliana protein match is: MMS ZWEI homologue 3 (TAIR:AT2G36060.2).
NP_566968.1
  • ubiquitin E2 variant 1D-4 (UEV1D-4); CONTAINS InterPro DOMAIN/s: Ubiquitin-conjugating enzyme/RWD-like (InterPro:IPR016135), Ubiquitin-conjugating enzyme, E2 (InterPro:IPR000608); BEST Arabidopsis thaliana protein match is: MMS ZWEI homologue 3 (TAIR:AT2G36060.1); Has 2665 Blast hits to 2665 proteins in 275 species: Archae - 0; Bacteria - 0; Metazoa - 1316; Fungi - 370; Plants - 595; Viruses - 0; Other Eukaryotes - 384 (source: NCBI BLink).
NP_850684.1
  • ubiquitin E2 variant 1D-4 (UEV1D-4); CONTAINS InterPro DOMAIN/s: Ubiquitin-conjugating enzyme/RWD-like (InterPro:IPR016135), Ubiquitin-conjugating enzyme, E2 (InterPro:IPR000608); BEST Arabidopsis thaliana protein match is: MMS ZWEI homologue 3 (TAIR:AT2G36060.2); Has 1301 Blast hits to 1301 proteins in 235 species: Archae - 0; Bacteria - 0; Metazoa - 663; Fungi - 165; Plants - 298; Viruses - 0; Other Eukaryotes - 175 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    19494369..19496147 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_115116.4 → NP_566968.1  ubiquitin E2 variant 1D-4 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_566968.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A8MSC0, Q3EAL0, Q9SVD7
    UniProtKB/TrEMBL
    A0A178VID5, A0A5S9XK78, A0A7G2EFT3
    Conserved Domains (1) summary
    cl00154
    Location:13 → 143
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...

  2. NM_001203144.1 → NP_001190073.1  ubiquitin E2 variant 1D-4 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001190073.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    F4J6Z1
    Conserved Domains (1) summary
    cl00154
    Location:17 → 143
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...

  3. NM_180353.2 → NP_850684.1  ubiquitin E2 variant 1D-4 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_850684.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178VKZ7, A0A7G2EFT3
    Conserved Domains (1) summary
    cl00154
    Location:13 → 144
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...

  4. NM_001084803.1 → NP_001078272.1  ubiquitin E2 variant 1D-4 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001078272.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9SVD7
    Conserved Domains (1) summary
    cl00154
    Location:9 → 89
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9SVD7.1

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