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EDD1 glycine-tRNA ligase [ Arabidopsis thaliana (thale cress) ]

Gene ID: 823966, updated on 18-Sep-2024

Summary

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Official Symbol
EDD1
Official Full Name
glycine-tRNA ligase
Primary source
TAIR:AT3G48110
Locus tag
AT3G48110
See related
Araport:AT3G48110
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
EDD; EMBRYO-DEFECTIVE-DEVELOPMENT 1; GLYCYL-TRNA SYNTHETASE
Summary
glycine-tRNA ligase
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Genomic context

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See EDD1 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
33
Sequence:
Chromosome: 3; NC_003074.8 (17762970..17771146)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene response regulator 5 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene serine/arginine-rich splicing factor Neighboring gene uncharacterized protein Neighboring gene miscRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Inactivation of a glycyl-tRNA synthetase leads to an arrest in plant embryo development. Uwer U, et al. Plant Cell, 1998 Aug. PMID 9707529, Free PMC Article
  2. The Arabidopsis organelle-localized glycyl-tRNA synthetase encoded by EMBRYO DEFECTIVE DEVELOPMENT1 is required for organ patterning. Moschopoulos A, et al. J Exp Bot, 2012 Sep. PMID 22791832, Free PMC Article
  3. Dual targeting is the rule for organellar aminoacyl-tRNA synthetases in Arabidopsis thaliana. Duchêne AM, et al. Proc Natl Acad Sci U S A, 2005 Nov 8. PMID 16251277, Free PMC Article
  4. Requirement of aminoacyl-tRNA synthetases for gametogenesis and embryo development in Arabidopsis. Berg M, et al. Plant J, 2005 Dec. PMID 16297076
  5. The oligomeric stromal proteome of Arabidopsis thaliana chloroplasts. Peltier JB, et al. Mol Cell Proteomics, 2006 Jan. PMID 16207701

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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NM_114680.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables glycine-tRNA ligase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables protein dimerization activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within embryo development ending in seed dormancy IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within glycyl-tRNA aminoacylation ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
acts_upstream_of_or_within regulation of embryonic development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast HDA PubMed 
located_in chloroplast IDA
Inferred from Direct Assay
more info
 PubMed 
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in chloroplast stroma HDA PubMed 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
glycine-tRNA ligase
NP_190394.3
  • EMBRYO-DEFECTIVE-DEVELOPMENT 1 (EDD1); FUNCTIONS IN: glycine-tRNA ligase activity; INVOLVED IN: regulation of embryonic development, glycyl-tRNA aminoacylation, embryo development ending in seed dormancy; LOCATED IN: mitochondrion, chloroplast stroma, chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Glycyl-tRNA synthetase, class IIc, beta subunit, N-terminal (InterPro:IPR002311), Glycyl-tRNA synthetase, class II, heterodimeric (InterPro:IPR006194), Glycyl-tRNA synthetase, class IIc, beta subunit (InterPro:IPR015944), Glycyl-tRNA synthetase, class IIc, alpha subunit (InterPro:IPR002310); Has 11308 Blast hits to 11293 proteins in 1754 species: Archae - 4; Bacteria - 6864; Metazoa - 4; Fungi - 1; Plants - 40; Viruses - 0; Other Eukaryotes - 4395 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    17762970..17771146
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_114680.4 → NP_190394.3  glycine-tRNA ligase [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_190394.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O23150, Q8L785, Q9SU73
    UniProtKB/TrEMBL
    A0A178VHQ7, A0A5S9XIT8
    Conserved Domains (3) summary
    PRK14908
    Location:70 → 1064
    PRK14908; glycyl-tRNA synthetase; Provisional
    pfam02091
    Location:73 → 348
    tRNA-synt_2e; Glycyl-tRNA synthetase alpha subunit
    pfam02092
    Location:386 → 928
    tRNA_synt_2f; Glycyl-tRNA synthetase beta subunit
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8L785.1

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