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UKL5 uridine kinase-like 5 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 822365, updated on 18-Sep-2024

Summary

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Official Symbol
UKL5
Official Full Name
uridine kinase-like 5
Primary source
TAIR:AT3G27440
Locus tag
AT3G27440
See related
Araport:AT3G27440
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
uridine kinase-like 5
Summary
One of the homologous genes predicted to encode proteins with UPRT domains (Uracil phosphoribosyltransferase). Five of these genes (At5g40870, At3g27190, At1g55810, At4g26510 and At3g27440) show a high level of identity, and are annotated as also containing a N-terminal uracil kinase (UK) domain. These genes are referred to as UKL1 (UK-like 1), UKL2, UKL3, UKL4 and UKL5, respectively.
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Genomic context

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See UKL5 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
12
Sequence:
Chromosome: 3; NC_003074.8 (10155438..10158215)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene bromodomain testis-specific protein Neighboring gene ECA1-like gametogenesis related family protein Neighboring gene N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein Neighboring gene miscRNA Neighboring gene SGF29 tudor-like domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
  2. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713
  3. Multi-omics network-based functional annotation of unknown Arabidopsis genes. Depuydt T, et al. Plant J, 2021 Nov. PMID 34562334

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables uracil phosphoribosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables uridine kinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in CTP salvage IEA
Inferred from Electronic Annotation
more info
  
involved_in UMP salvage IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
uridine kinase-like 5
NP_189380.1
  • uridine kinase-like 5 (UKL5); FUNCTIONS IN: uracil phosphoribosyltransferase activity, kinase activity, phosphotransferase activity, alcohol group as acceptor, ATP binding; INVOLVED IN: biosynthetic process, metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 6 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Phosphoribulokinase/uridine kinase (InterPro:IPR006083), Uridine kinase (InterPro:IPR000764); BEST Arabidopsis thaliana protein match is: uridine kinase-like 4 (TAIR:AT4G26510.2); Has 13214 Blast hits to 13202 proteins in 2627 species: Archae - 217; Bacteria - 10041; Metazoa - 552; Fungi - 516; Plants - 596; Viruses - 2; Other Eukaryotes - 1290 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    10155438..10158215
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001338873.1 → NP_001326122.1  uridine kinase-like 5 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178VGZ4, A0A1I9LNB3

  2. NM_113659.2 → NP_189380.1  uridine kinase-like 5 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_189380.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9LTY6
    UniProtKB/TrEMBL
    A0A178VGZ4, A0A5S9XGX8
    Conserved Domains (2) summary
    cd02023
    Location:31 → 228
    UMPK; Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway, ...
    pfam14681
    Location:246 → 447
    UPRTase; Uracil phosphoribosyltransferase

  3. NM_001338874.1 → NP_001326121.1  uridine kinase-like 5 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178VGZ4, A0A1I9LNB2
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LTY6.1

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