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SNL1 SIN3-like 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 821265, updated on 18-Sep-2024

Summary

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Official Symbol
SNL1
Official Full Name
SIN3-like 1
Primary source
TAIR:AT3G01320
Locus tag
AT3G01320
See related
Araport:AT3G01320
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
SIN3-like 1; T22N4.5; T22N4_5
Summary
Encodes SIN3-like 1, a homolog of the transcriptional repressor SIN3 (AT1G24190).
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Genomic context

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See SNL1 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
22
Sequence:
Chromosome: 3; NC_003074.8 (106294..113679)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene miscRNA Neighboring gene uncharacterized protein Neighboring gene ECA1-like gametogenesis related family protein Neighboring gene ECA1 gametogenesis related family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Arabidopsis paired amphipathic helix proteins SNL1 and SNL2 redundantly regulate primary seed dormancy via abscisic acid-ethylene antagonism mediated by histone deacetylation. Wang Z, et al. Plant Cell, 2013 Jan. PMID 23371947, Free PMC Article
  2. PAH-domain-specific interactions of the Arabidopsis transcription coregulator SIN3-LIKE1 (SNL1) with telomere-binding protein 1 and ALWAYS EARLY2 Myb-DNA binding factors. Bowen AJ, et al. J Mol Biol, 2010 Feb 5. PMID 19962994
  3. Arabidopsis RPD3-like histone deacetylases form multiple complexes involved in stress response. Feng C, et al. J Genet Genomics, 2021 May 20. PMID 34144927
  4. CrY2H-seq: a massively multiplexed assay for deep-coverage interactome mapping. Wanamaker SA, et al. Nat Methods, 2017 Aug. PMID 28650476, Free PMC Article
  5. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. SNL1 and SNL2 regulate seed dormancy by mediating the abscisic acid (ABA)-ethylene antagonism in Arabidopsis. SNL1 and SNL2 could represent a cross-link point of the ABA and ethylene pathways in the regulation of seed dormancy.
    Title: Arabidopsis paired amphipathic helix proteins SNL1 and SNL2 redundantly regulate primary seed dormancy via abscisic acid-ethylene antagonism mediated by histone deacetylation.
  2. full-length SNL1 was shown to repress transcription in a histone-deacetylase-dependent manner, demonstrating the conserved nature of SIN3 function
    Title: PAH-domain-specific interactions of the Arabidopsis transcription coregulator SIN3-LIKE1 (SNL1) with telomere-binding protein 1 and ALWAYS EARLY2 Myb-DNA binding factors.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001202860.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in negative regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
part_of Sin3-type complex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
SIN3-like 1
NP_001189789.1
  • SIN3-like 1 (SNL1); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: regulation of transcription, DNA-dependent; LOCATED IN: nucleus; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Histone deacetylase interacting (InterPro:IPR013194), Paired amphipathic helix (InterPro:IPR003822); BEST Arabidopsis thaliana protein match is: SIN3-like 2 (TAIR:AT5G15020.2).
NP_186781.4
  • SIN3-like 1 (SNL1); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: regulation of transcription, DNA-dependent; LOCATED IN: nucleus; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Histone deacetylase interacting (InterPro:IPR013194), Paired amphipathic helix (InterPro:IPR003822); BEST Arabidopsis thaliana protein match is: SIN3-like 2 (TAIR:AT5G15020.2); Has 8924 Blast hits to 4656 proteins in 481 species: Archae - 44; Bacteria - 2736; Metazoa - 2712; Fungi - 1300; Plants - 581; Viruses - 181; Other Eukaryotes - 1370 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    106294..113679
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_110998.5 → NP_186781.4  SIN3-like 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_186781.4

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9SRH9
    UniProtKB/TrEMBL
    A0A178VAF5, A0A654FDK6
    Conserved Domains (5) summary
    smart00761
    Location:467 → 563
    HDAC_interact; Histone deacetylase (HDAC) interacting
    COG5602
    Location:13 → 672
    Sin3; Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]
    pfam02671
    Location:74 → 118
    PAH; Paired amphipathic helix repeat
    pfam16879
    Location:1100 → 1343
    Sin3a_C; C-terminal domain of Sin3a protein
    cl11968
    Location:46 → 144
    harmonin_N_like; N-terminal protein-binding module of harmonin and similar domains, also known as HHD (harmonin homology domain)

  2. NM_001202860.2 → NP_001189789.1  SIN3-like 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001189789.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178VAF5, A0A654FDK6, F4JAQ8
    Conserved Domains (5) summary
    smart00761
    Location:455 → 551
    HDAC_interact; Histone deacetylase (HDAC) interacting
    COG5602
    Location:13 → 660
    Sin3; Histone deacetylase complex, regulatory component SIN3 [Chromatin structure and dynamics]
    pfam02671
    Location:74 → 118
    PAH; Paired amphipathic helix repeat
    pfam16879
    Location:1088 → 1331
    Sin3a_C; C-terminal domain of Sin3a protein
    cl11968
    Location:46 → 144
    harmonin_N_like; N-terminal protein-binding module of harmonin and similar domains, also known as HHD (harmonin homology domain)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9SRH9.2

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