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NP3 NPK1-related protein kinase 3 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 819774, updated on 18-Sep-2024

Summary

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Official Symbol
NP3
Official Full Name
NPK1-related protein kinase 3
Primary source
TAIR:AT3G06030
Locus tag
AT3G06030
See related
Araport:AT3G06030
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ANP3; AtANP3; F24F17.1; F24F17_1; MAPKKK12; NPK1-related protein kinase 3
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Genomic context

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See NP3 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
17
Sequence:
Chromosome: 3; NC_003074.8 (1818732..1822858, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene SNF2/Brahma-type chromatin-remodeling protein CHR12 Neighboring gene uncharacterized protein Neighboring gene FANTASTIC four-like protein (DUF3049) Neighboring gene Glycoprotein membrane precursor GPI-anchored Neighboring gene Ribosomal protein L12/ ATP-dependent Clp protease adaptor protein ClpS family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The intracellular ROS accumulation in elicitor-induced immunity requires the multiple organelle-targeted Arabidopsis NPK1-related protein kinases. Marti L, et al. Plant Cell Environ, 2021 Mar. PMID 33314180
  2. Proteomic and biochemical analyses show a functional network of proteins involved in antioxidant defense of the Arabidopsis anp2anp3 double mutant. Takáč T, et al. J Proteome Res, 2014 Dec 5. PMID 25325904, Free PMC Article
  3. Arabidopsis homologs of nucleus- and phragmoplast-localized kinase 2 and 3 and mitogen-activated protein kinase 4 are essential for microtubule organization. Beck M, et al. Plant Cell, 2010 Mar. PMID 20215588, Free PMC Article
  4. AtMPK4 is required for male-specific meiotic cytokinesis in Arabidopsis. Zeng Q, et al. Plant J, 2011 Sep. PMID 21575092
  5. Autophosphorylation profiling of Arabidopsis protein kinases using the cell-free system. Nemoto K, et al. Phytochemistry, 2011 Jul. PMID 21477822

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The intracellular ROS accumulation in elicitor-induced immunity requires the multiple organelle-targeted Arabidopsis NPK1-related protein kinases.
    Title: The intracellular ROS accumulation in elicitor-induced immunity requires the multiple organelle-targeted Arabidopsis NPK1-related protein kinases.
  2. Data show that the functional network of proteins involved in antioxidant defense in the MAPK kinase kinases (MAPKKK) anp2anp3 mutant was physiologically linked with the increased resistance of mutant seedlings against paraquat treatment.
    Title: Proteomic and biochemical analyses show a functional network of proteins involved in antioxidant defense of the Arabidopsis anp2anp3 double mutant.
  3. ANP2/ANP3, MPK4, and the MT-associated protein MAP65-1 are involved in microtubule-dependent cell growth mechanisms.
    Title: Arabidopsis homologs of nucleus- and phragmoplast-localized kinase 2 and 3 and mitogen-activated protein kinase 4 are essential for microtubule organization.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_111477.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables MAP kinase kinase kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein serine/threonine kinase activity HDA PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within cortical microtubule organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cortical microtubule organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within protein autophosphorylation HDA PubMed 
Component Evidence Code Pubs
located_in apoplast HDA PubMed 
located_in plasma membrane ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
NPK1-related protein kinase 3
NP_187254.1
  • NPK1-related protein kinase 3 (NP3); FUNCTIONS IN: protein serine/threonine kinase activity, protein kinase activity, kinase activity, ATP binding; INVOLVED IN: cortical microtubule organization; LOCATED IN: apoplast; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Mitogen activated protein kinase kinase kinase 3 (InterPro:IPR015748), Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: NPK1-related protein kinase 1 (TAIR:AT1G09000.1); Has 135037 Blast hits to 132652 proteins in 4867 species: Archae - 156; Bacteria - 15291; Metazoa - 50641; Fungi - 13369; Plants - 33230; Viruses - 554; Other Eukaryotes - 21796 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    1818732..1822858 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_111477.4 → NP_187254.1  NPK1-related protein kinase 3 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_187254.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O22042, Q9SFG7
    UniProtKB/TrEMBL
    A0A178VLY7
    Conserved Domains (2) summary
    smart00220
    Location:68 → 330
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd06606
    Location:67 → 330
    STKc_MAPKKK; Catalytic domain of the Serine/Threonine Kinase, Mitogen-Activated Protein Kinase Kinase Kinase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O22042.1

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