U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

NF-YA2 nuclear factor Y, subunit A2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 819738, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
NF-YA2
Official Full Name
nuclear factor Y, subunit A2
Primary source
TAIR:AT3G05690
Locus tag
AT3G05690
See related
Araport:AT3G05690
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
''nuclear factor Y; ATHAP2B; AtNF-YA2; F18C1.4; F18C1_4; HAP2B; HEME ACTIVATOR PROTEIN (YEAST) HOMOLOG 2B; nuclear factor Y; subunit A2; subunit A2''; UNE8; UNFERTILIZED EMBRYO SAC 8
Summary
Encodes a subunit of CCAAT-binding complex, binds to CCAAT box motif present in some plant promoter sequences. One of three members of this class (HAP2A, HAP2B, HAP2C), it is expressed in vegetative and reproductive tissues.
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See NF-YA2 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
5
Sequence:
Chromosome: 3; NC_003074.8 (1676504..1679061, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene embryo defective 2016 Neighboring gene Cystatin/monellin superfamily protein Neighboring gene Drought-responsive family protein Neighboring gene ncRNA Neighboring gene syntaxin of plants 43 Neighboring gene importin alpha isoform 7

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Transcription factors NF-YA2 and NF-YA10 regulate leaf growth via auxin signaling in Arabidopsis. Zhang M, et al. Sci Rep, 2017 May 3. PMID 28469131, Free PMC Article
  2. Stress-induced early flowering is mediated by miR169 in Arabidopsis thaliana. Xu MY, et al. J Exp Bot, 2014 Jan. PMID 24336445
  3. A miR169 isoform regulates specific NF-YA targets and root architecture in Arabidopsis. Sorin C, et al. New Phytol, 2014 Jun. PMID 24533947
  4. Multiple genes encoding the conserved CCAAT-box transcription factor complex are expressed in Arabidopsis. Edwards D, et al. Plant Physiol, 1998 Jul. PMID 9662544, Free PMC Article
  5. Arabidopsis DPB3-1, a DREB2A interactor, specifically enhances heat stress-induced gene expression by forming a heat stress-specific transcriptional complex with NF-Y subunits. Sato H, et al. Plant Cell, 2014 Dec. PMID 25490919, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Findings showed leaf development was regulated by NF-YA2 and NF-YA10 through the auxin-signaling pathway and may provide a new insight into the genetic engineering of vegetables biomass and crop productivity.
    Title: Transcription factors NF-YA2 and NF-YA10 regulate leaf growth via auxin signaling in Arabidopsis.
  2. The authors identified a regulatory node involving the particular miR169defg isoform and NF-YA2 and NF-YA10 genes that acts in the control of primary root growth.
    Title: A miR169 isoform regulates specific NF-YA targets and root architecture in Arabidopsis.
  3. The miR169 family regulates stress-induced flowering by repressing the AtNF-YA transcription factor, which in turn reduces the expression of FLOWERING LOCUS C (FLC), allowing for the expression of FLC target genes
    Title: Stress-induced early flowering is mediated by miR169 in Arabidopsis thaliana.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help
NM_111443.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables DNA-binding transcription factor activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
enables DNA-binding transcription factor activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within double fertilization forming a zygote and endosperm IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within regulation of DNA-templated transcription ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in response to heat IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
part_of CCAAT-binding factor complex ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus ISM
Inferred from Sequence Model
more info
  

General protein information

Go to the top of the page Help
Preferred Names
nuclear factor Y, subunit A2
NP_187220.1
  • ''nuclear factor Y, subunit A2'' (NF-YA2); CONTAINS InterPro DOMAIN/s: CCAAT-binding transcription factor, subunit B (InterPro:IPR001289); BEST Arabidopsis thaliana protein match is: nuclear factor Y, subunit A10 (TAIR:AT5G06510.2); Has 655 Blast hits to 655 proteins in 159 species: Archae - 0; Bacteria - 0; Metazoa - 138; Fungi - 132; Plants - 359; Viruses - 0; Other Eukaryotes - 26 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    1676504..1679061 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001337602.1 → NP_001327635.1  nuclear factor Y, subunit A2 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178VK23, A0A1I9LSX7, A0A5S9XA32, Q0WS51

  2. NM_111443.4 → NP_187220.1  nuclear factor Y, subunit A2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_187220.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O23631, Q9M9X4
    UniProtKB/TrEMBL
    A0A178VK23, A0A5S9XA32, A0A654F9Q6, Q0WS51, Q147N1
    Conserved Domains (1) summary
    smart00521
    Location:133 → 198
    CBF; CCAAT-Binding transcription Factor
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9M9X4.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools