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PIP1B plasma membrane intrinsic protein 1B [ Arabidopsis thaliana (thale cress) ]

Gene ID: 819204, updated on 18-Sep-2024

Summary

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Official Symbol
PIP1B
Official Full Name
plasma membrane intrinsic protein 1B
Primary source
TAIR:AT2G45960
Locus tag
AT2G45960
See related
Araport:AT2G45960
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATHH2; F4I18.6; NAMED PLASMA MEMBRANE INTRINSIC PROTEIN 1;2; PIP1;2; plasma membrane intrinsic protein 1B; TMP-A; TRANSMEMBRANE PROTEIN A
Summary
a member of the plasma membrane intrinsic protein subfamily PIP1. localizes to the plasma membrane and exhibits water transport activity in Xenopus oocyte. expressed ubiquitously and protein level decreases slightly during leaf development.
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Genomic context

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See PIP1B in Genome Data Viewer
Location:
chromosome: 2
Exon count:
3
Sequence:
Chromosome: 2; NC_003071.7 (18910081..18911982)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene hypothetical protein (DUF295) Neighboring gene ncRNA Neighboring gene SKP1-like 20 Neighboring gene cytochrome P450, family 86, subfamily A, polypeptide 8 Neighboring gene mesoderm induction early response protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Overexpression of a plasma membrane aquaporin in transgenic tobacco improves plant vigor under favorable growth conditions but not under drought or salt stress. Aharon R, et al. Plant Cell, 2003 Feb. PMID 12566583, Free PMC Article
  2. T-DNA insertion in aquaporin gene AtPIP1;2 generates transcription profiles reminiscent of a low CO2 response. Boudichevskaia A, et al. Plant Cell Environ, 2015 Nov. PMID 25850563
  3. A PIP1 aquaporin contributes to hydrostatic pressure-induced water transport in both the root and rosette of Arabidopsis. Postaire O, et al. Plant Physiol, 2010 Mar. PMID 20034965, Free PMC Article
  4. The Arabidopsis thaliana aquaporin AtPIP1;2 is a physiologically relevant CO₂ transport facilitator. Heckwolf M, et al. Plant J, 2011 Sep. PMID 21564354
  5. The Arabidopsis aquaporin PIP1;2 rules cellular CO(2) uptake. Uehlein N, et al. Plant Cell Environ, 2012 Jun. PMID 22150826

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Results identified 2 members of the receptor-like kinase (RLK) family (RKL1 (At1g48480) and Feronia (At3g51550)) differentially modulate PIP1;2 and PIP2;1 activity through distinct molecular mechanisms.
    Title: Novel Aquaporin Regulatory Mechanisms Revealed by Interactomics.
  2. The AtPIP1;2 function in plant physiology is to facilitate CO2 diffusion.
    Title: T-DNA insertion in aquaporin gene AtPIP1;2 generates transcription profiles reminiscent of a low CO2 response.
  3. The AtPIP1;2 gene product limits CO diffusion and photosynthesis in leaves.
    Title: The Arabidopsis thaliana aquaporin AtPIP1;2 is a physiologically relevant CO₂ transport facilitator.
  4. Cellular CO(2) transport was not limited by unstirred layer effects but was dependent on the expression of the aquaporin AtPIP1;2.
    Title: The Arabidopsis aquaporin PIP1;2 rules cellular CO(2) uptake.
  5. The expression of both AtPIP1;2 and AtPIP2;1 oscillated with the circadian rhythm under low light conditions in wild-type seedlings, but not in the elf3 mutant.
    Title: The circadian clock modulates water dynamics and aquaporin expression in Arabidopsis roots.
  6. AtPIP1;2 significantly contributes to the hydraulic conductivity of both roots and rosette.
    Title: A PIP1 aquaporin contributes to hydrostatic pressure-induced water transport in both the root and rosette of Arabidopsis.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001084597.1
NM_001084598.1
NM_130159.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables channel activity IEA
Inferred from Electronic Annotation
more info
  
enables water channel activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables water channel activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within carbon dioxide transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to salt stress IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within response to water deprivation IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within response to water deprivation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within water transport IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol HDA PubMed 
located_in plant-type vacuole HDA PubMed 
located_in plasma membrane HDA PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
plasma membrane intrinsic protein 1B
NP_001078066.1
  • plasma membrane intrinsic protein 1B (PIP1B); FUNCTIONS IN: water channel activity; INVOLVED IN: response to water deprivation, response to salt stress, transport, water transport; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Major intrinsic protein, conserved site (InterPro:IPR022357), Aquaporin (InterPro:IPR012269), Major intrinsic protein (InterPro:IPR000425); BEST Arabidopsis thaliana protein match is: plasma membrane intrinsic protein 1;4 (TAIR:AT4G00430.1); Has 10376 Blast hits to 10338 proteins in 2169 species: Archae - 101; Bacteria - 4994; Metazoa - 1330; Fungi - 442; Plants - 2464; Viruses - 0; Other Eukaryotes - 1045 (source: NCBI BLink).
NP_001078067.1
  • plasma membrane intrinsic protein 1B (PIP1B); FUNCTIONS IN: water channel activity; INVOLVED IN: response to water deprivation, response to salt stress, transport, water transport; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Major intrinsic protein, conserved site (InterPro:IPR022357), Aquaporin (InterPro:IPR012269), Major intrinsic protein (InterPro:IPR000425); BEST Arabidopsis thaliana protein match is: plasma membrane intrinsic protein 1;4 (TAIR:AT4G00430.1); Has 10384 Blast hits to 10346 proteins in 2170 species: Archae - 101; Bacteria - 5000; Metazoa - 1330; Fungi - 442; Plants - 2465; Viruses - 0; Other Eukaryotes - 1046 (source: NCBI BLink).
NP_182120.1
  • plasma membrane intrinsic protein 1B (PIP1B); FUNCTIONS IN: water channel activity; INVOLVED IN: response to water deprivation, response to salt stress, transport, water transport; LOCATED IN: anchored to plasma membrane, plasma membrane, chloroplast, vacuole, membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Major intrinsic protein, conserved site (InterPro:IPR022357), Aquaporin (InterPro:IPR012269), Major intrinsic protein (InterPro:IPR000425); BEST Arabidopsis thaliana protein match is: plasma membrane intrinsic protein 1;4 (TAIR:AT4G00430.1); Has 10777 Blast hits to 10745 proteins in 2215 species: Archae - 97; Bacteria - 5153; Metazoa - 1470; Fungi - 452; Plants - 2515; Viruses - 2; Other Eukaryotes - 1088 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    18910081..18911982
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_130159.4 → NP_182120.1  plasma membrane intrinsic protein 1B [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_182120.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q06611, Q8L5V4
    UniProtKB/TrEMBL
    A0A178VYL1, A0A384KNK4, A0A7G2EE24, D9IX99
    Conserved Domains (1) summary
    pfam00230
    Location:44 → 273
    MIP; Major intrinsic protein

  2. NM_001084597.1 → NP_001078066.1  plasma membrane intrinsic protein 1B [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001078066.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A7G2EE24, B9DFR9
    Conserved Domains (1) summary
    pfam00230
    Location:44 → 255
    MIP; Major intrinsic protein

  3. NM_001084598.1 → NP_001078067.1  plasma membrane intrinsic protein 1B [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001078067.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A7G2EE24, A8MRW1
    Conserved Domains (1) summary
    pfam00230
    Location:44 → 261
    MIP; Major intrinsic protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q06611.1

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