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Haloacid dehalogenase-like hydrolase (HAD) superfamily protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 818456, updated on 18-Sep-2024

Summary

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Official Full Name
Haloacid dehalogenase-like hydrolase (HAD) superfamily protein
Primary source
TAIR:AT2G38740
Locus tag
AT2G38740
See related
Araport:AT2G38740
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
T6A23.6; T6A23_6
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Genomic context

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Location:
chromosome: 2
Exon count:
4
Sequence:
Chromosome: 2; NC_003071.7 (16194326..16196183, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene microtubule-associated protein 65-5 Neighboring gene Cyclophilin-like peptidyl-prolyl cis-trans isomerase family protein Neighboring gene annexin 4 Neighboring gene annexin 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The kinetic analysis of the substrate specificity of motif 5 in a HAD hydrolase-type phosphosugar phosphatase of Arabidopsis thaliana. Caparrós-Martín JA, et al. Planta, 2014 Sep. PMID 24915748
  2. HAD hydrolase function unveiled by substrate screening: enzymatic characterization of Arabidopsis thaliana subclass I phosphosugar phosphatase AtSgpp. Caparrós-Martín JA, et al. Planta, 2013 Apr. PMID 23179445, Free PMC Article
  3. Sequence Determinants of Substrate Ambiguity in a HAD Phosphosugar Phosphatase of Arabidopsis Thaliana. Caparrós-Martín JA, et al. Biology (Basel), 2019 Oct 9. PMID 31601035, Free PMC Article
  4. A high content in lipid-modified peripheral proteins and integral receptor kinases features in the arabidopsis plasma membrane proteome. Marmagne A, et al. Mol Cell Proteomics, 2007 Nov. PMID 17644812
  5. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Mutation A69M, changes the pH dependence of AtSgpp catalysis, and mutant protein AtSgpp-H72K was inactive in phosphomonoester dephosphorylation.
    Title: The kinetic analysis of the substrate specificity of motif 5 in a HAD hydrolase-type phosphosugar phosphatase of Arabidopsis thaliana.
  2. functions in housekeeping detoxification, modulation of sugar-phosphate balance and Pi homeostasis
    Title: HAD hydrolase function unveiled by substrate screening: enzymatic characterization of Arabidopsis thaliana subclass I phosphosugar phosphatase AtSgpp.
Submit: New GeneRIF Correction

General gene information

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Homology

NM_129431.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables sugar-phosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within dephosphorylation IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  
located_in plasma membrane HDA PubMed 

General protein information

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Preferred Names
Haloacid dehalogenase-like hydrolase (HAD) superfamily protein
NP_565895.1
  • Haloacid dehalogenase-like hydrolase (HAD) superfamily protein; FUNCTIONS IN: hydrolase activity, catalytic activity; INVOLVED IN: metabolic process; LOCATED IN: plasma membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Haloacid dehalogenase-like hydrolase (InterPro:IPR005834), Haloacid dehydrogenase/epoxide hydrolase (InterPro:IPR005833), HAD-superfamily hydrolase, subfamily IA, variant 3 (InterPro:IPR006402); BEST Arabidopsis thaliana protein match is: haloacid dehalogenase-like hydrolase family protein (TAIR:AT1G56500.1); Has 17978 Blast hits to 17978 proteins in 2581 species: Archae - 265; Bacteria - 14433; Metazoa - 167; Fungi - 429; Plants - 387; Viruses - 3; Other Eukaryotes - 2294 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    16194326..16196183 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_129431.2 → NP_565895.1  Haloacid dehalogenase-like hydrolase (HAD) superfamily protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_565895.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q93ZP4, Q9ZVJ5
    UniProtKB/TrEMBL
    A0A5S9X596, A0A654F042
    Conserved Domains (1) summary
    PLN02770
    Location:1 → 244
    PLN02770; haloacid dehalogenase-like hydrolase family protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9ZVJ5.2

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