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MBAC1 Mitochondrial substrate carrier family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 817949, updated on 18-Sep-2024

Summary

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Official Symbol
MBAC1
Official Full Name
Mitochondrial substrate carrier family protein
Primary source
TAIR:AT2G33820
Locus tag
AT2G33820
See related
Araport:AT2G33820
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATMBAC1; BAC1; T1B8.12; T1B8_12
Summary
encodes a mitochondrial ornithine transporter which exports ornithine from the mitochondrion to the cytosol
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Genomic context

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See MBAC1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
8
Sequence:
Chromosome: 2; NC_003071.7 (14306293..14308367, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene squamosa promoter binding protein-like 3 Neighboring gene Dormancy/auxin associated family protein Neighboring gene Zinc finger C-x8-C-x5-C-x3-H type family protein Neighboring gene Tyrosyl-tRNA synthetase, class Ib, bacterial/mitochondrial

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Arabidopsis mitochondria have two basic amino acid transporters with partially overlapping specificities and differential expression in seedling development. Palmieri L, et al. Biochim Biophys Acta, 2006 Sep-Oct. PMID 16730327
  2. Identification of a mitochondrial transporter for basic amino acids in Arabidopsis thaliana by functional reconstitution into liposomes and complementation in yeast. Hoyos ME, et al. Plant J, 2003 Mar. PMID 12631327
  3. A user-friendly platform for yeast two-hybrid library screening using next generation sequencing. Erffelinck ML, et al. PLoS One, 2018. PMID 30576311, Free PMC Article
  4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Both BAC1 and BAC2 displayed highest affinity for arginine with similar Km and Vmax. However, BAC2 transported citrulline for which BAC1 had little or no affinity. Furthermore, BAC2 was less stereospecific than BAC1.
    Title: Arabidopsis mitochondria have two basic amino acid transporters with partially overlapping specificities and differential expression in seedling development.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_001336471.1
NM_001336472.1
NM_001336473.1
NM_128941.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables L-histidine transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables L-lysine transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables L-ornithine transmembrane transporter activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
Mitochondrial substrate carrier family protein
NP_180938.2
  • MBAC1; FUNCTIONS IN: arginine transmembrane transporter activity, L-histidine transmembrane transporter activity, L-lysine transmembrane transporter activity, L-ornithine transmembrane transporter activity, binding; INVOLVED IN: transport, mitochondrial transport, transmembrane transport; LOCATED IN: mitochondrial inner membrane, membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Mitochondrial substrate carrier (InterPro:IPR001993), Mitochondrial substrate/solute carrier (InterPro:IPR018108), Adenine nucleotide translocator 1 (InterPro:IPR002113); BEST Arabidopsis thaliana protein match is: Mitochondrial substrate carrier family protein (TAIR:AT5G46800.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    14306293..14308367 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_128941.3 → NP_180938.2  Mitochondrial substrate carrier family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_180938.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P93016, Q84UC7
    UniProtKB/TrEMBL
    A0A178VWG0, A0A5S9X479
    Conserved Domains (1) summary
    pfam00153
    Location:13 → 104
    Mito_carr; Mitochondrial carrier protein

  2. NM_001336472.1 → NP_001324476.1  Mitochondrial substrate carrier family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8B094, A0A5S9X479

  3. NM_001336471.1 → NP_001324477.1  Mitochondrial substrate carrier family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8B093

  4. NM_001336473.1 → NP_001324478.1  Mitochondrial substrate carrier family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A1P8B0A2
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q84UC7.1

Gene LinkOut

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