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5PTase14 endonuclease/exonuclease/phosphatase family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 817740, updated on 18-Sep-2024

Summary

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Official Symbol
5PTase14
Official Full Name
endonuclease/exonuclease/phosphatase family protein
Primary source
TAIR:AT2G31830
Locus tag
AT2G31830
See related
Araport:AT2G31830
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F20M17.13; F20M17_13; inositol-polyphosphate 5-phosphatase 14
Summary
Encodes a 5-inositol-polyphosphate phosphatase, that, in vitro, shows some activity against Ins(1,4,5)P3 and PI(3,4,5)P3, but even higher activity against PI(4,5)P2
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Genomic context

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See 5PTase14 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
11
Sequence:
Chromosome: 2; NC_003071.7 (13532483..13537800, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene UDP-Glycosyltransferase superfamily protein Neighboring gene Integrin-linked protein kinase family Neighboring gene ACT domain-containing small subunit of acetolactate synthase protein Neighboring gene Ankyrin repeat family protein Neighboring gene Thioredoxin superfamily protein Neighboring gene uncharacterized protein Neighboring gene miscRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables inositol-1,4,5-trisphosphate 5-phosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity IEA
Inferred from Electronic Annotation
more info
  
enables phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within dephosphorylation IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within inositol phosphate metabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in phosphatidylinositol dephosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
endonuclease/exonuclease/phosphatase family protein
NP_001189651.1
  • endonuclease/exonuclease/phosphatase family protein; FUNCTIONS IN: inositol or phosphatidylinositol phosphatase activity; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Inositol polyphosphate related phosphatase (InterPro:IPR000300), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat (InterPro:IPR001680), Endonuclease/exonuclease/phosphatase (InterPro:IPR005135), Quinoprotein amine dehydrogenase, beta chain-like (InterPro:IPR011044); BEST Arabidopsis thaliana protein match is: Endonuclease/exonuclease/phosphatase family protein (TAIR:AT1G05630.2).
NP_180742.1
  • endonuclease/exonuclease/phosphatase family protein; FUNCTIONS IN: inositol or phosphatidylinositol phosphatase activity; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Inositol polyphosphate related phosphatase (InterPro:IPR000300), WD40 repeat (InterPro:IPR001680), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), Endonuclease/exonuclease/phosphatase (InterPro:IPR005135), Quinoprotein amine dehydrogenase, beta chain-like (InterPro:IPR011044); BEST Arabidopsis thaliana protein match is: Endonuclease/exonuclease/phosphatase family protein (TAIR:AT1G05630.2); Has 2284 Blast hits to 2227 proteins in 249 species: Archae - 0; Bacteria - 34; Metazoa - 850; Fungi - 543; Plants - 566; Viruses - 0; Other Eukaryotes - 291 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    13532483..13537800 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_128741.3 → NP_180742.1  endonuclease/exonuclease/phosphatase family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_180742.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9SKB7
    UniProtKB/TrEMBL
    A0A5S9X3J9, A0A654EXZ0
    Conserved Domains (4) summary
    cd09074
    Location:580 → 926
    INPP5c; Catalytic domain of inositol polyphosphate 5-phosphatases
    COG2319
    Location:218 → 384
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:451 → 484
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:449 → 533
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  2. NM_001202722.1 → NP_001189651.1  endonuclease/exonuclease/phosphatase family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001189651.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A654EXZ0, F4IRT2
    Conserved Domains (4) summary
    cd09074
    Location:580 → 926
    INPP5c; Catalytic domain of inositol polyphosphate 5-phosphatases
    COG2319
    Location:218 → 384
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:451 → 484
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:449 → 533
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  3. NM_001336348.1 → NP_001324125.1  endonuclease/exonuclease/phosphatase family protein [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178VTH3, A0A1P8AZ51
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9SKB7.1

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