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Rpl19 ribosomal protein L19 [ Rattus norvegicus (Norway rat) ]

Gene ID: 81767, updated on 17-Aug-2024

Summary

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Symbol
Rpl19provided by RGD
Full Name
ribosomal protein L19provided by RGD
Primary source
RGD:621183
See related
EnsemblRapid:ENSRNOG00000004741 AllianceGenome:RGD:621183
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Enables 5.8S rRNA binding activity and large ribosomal subunit rRNA binding activity. Involved in liver regeneration. Part of cytosolic large ribosomal subunit. Orthologous to human RPL19 (ribosomal protein L19). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Thymus (RPKM 3543.9), Spleen (RPKM 3420.7) and 9 other tissues See more
Orthologs
human mouse all
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Genomic context

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See Rpl19 in Genome Data Viewer
Location:
10q31
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (83514509..83522352)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (83022503..83026030)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (85978691..85981979)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134480866 Neighboring gene transfer RNA cysteine (anticodon GCA) 37 Neighboring gene ADP-ribosylation factor like GTPase 5C Neighboring gene calcium voltage-gated channel auxiliary subunit beta 1 Neighboring gene SH3 and cysteine rich domain 2 Neighboring gene uncharacterized LOC102548674

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. The L19 ribosomal protein gene (RPL19): gene organization, chromosomal mapping, and novel promoter region. Davies B, et al. Genomics, 1995 Jan 20. PMID 7789970
  2. The primary structure of rat ribosomal protein L19. A determination from the sequence of nucleotides in a cDNA and from the sequence of amino acids in the protein. Chan YL, et al. J Biol Chem, 1987 Jan 25. PMID 3542997
  3. A strategy to detect and isolate an intron-containing gene in the presence of multiple processed pseudogenes. Davies B, et al. Proc Natl Acad Sci U S A, 1989 Sep. PMID 2771953, Free PMC Article
  4. Identification by affinity chromatography of the eukaryotic ribosomal proteins that bind to 5.8 S ribosomal ribonucleic acid. Ulbrich N, et al. J Biol Chem, 1979 Sep 10. PMID 468846
  5. Retinoic acid receptors and retinoids are up-regulated in the developing and adult rat prostate by neonatal estrogen exposure. Prins GS, et al. Endocrinology, 2002 Sep. PMID 12193579

See all (21) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables 5.8S rRNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables large ribosomal subunit rRNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in cytoplasmic translation ISO
Inferred from Sequence Orthology
more info
  
involved_in liver regeneration IEP
Inferred from Expression Pattern
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
part_of cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cytosolic large ribosomal subunit IDA
Inferred from Direct Assay
more info
 PubMed 
part_of cytosolic large ribosomal subunit IEA
Inferred from Electronic Annotation
more info
  
part_of cytosolic large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
located_in cytosolic ribosome ISO
Inferred from Sequence Orthology
more info
  
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
  
is_active_in synapse ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
large ribosomal subunit protein eL19
Names
60S ribosomal protein L19
60S ribosomal protein L19-like
NP_112365.1
XP_038942866.1
XP_038942867.1
XP_063126021.1
XP_063126022.1
XP_063126023.1
XP_063126024.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031103.1 → NP_112365.1  large ribosomal subunit protein eL19

    See identical proteins and their annotated locations for NP_112365.1

    Status: PROVISIONAL

    Source sequence(s)
    X82202
    UniProtKB/Swiss-Prot
    P84100
    UniProtKB/TrEMBL
    A0A8I6G776, A6HIP8
    Related
    ENSRNOP00000100931.1, ENSRNOT00000146075.1
    Conserved Domains (1) summary
    cd01417
    Location:4 → 167
    Ribosomal_L19e_E; Ribosomal protein L19e, eukaryotic. L19e is found in the large ribosomal subunit of eukaryotes and archaea. L19e is distinct from the ribosomal subunit L19, which is found in prokaryotes. It consists of two small globular domains connected by an ...

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    83514509..83522352
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063269954.1 → XP_063126024.1  large ribosomal subunit protein eL19 isoform X2

    UniProtKB/TrEMBL
    A0A8I6G776
    Related
    ENSRNOP00000110363.1, ENSRNOT00000135750.1

  2. XM_063269952.1 → XP_063126022.1  large ribosomal subunit protein eL19 isoform X1

    UniProtKB/Swiss-Prot
    P84100
    UniProtKB/TrEMBL
    A0A8I6G776, A6HIP8

  3. XM_063269953.1 → XP_063126023.1  large ribosomal subunit protein eL19 isoform X1

    UniProtKB/Swiss-Prot
    P84100
    UniProtKB/TrEMBL
    A0A8I6G776, A6HIP8

  4. XM_063269951.1 → XP_063126021.1  large ribosomal subunit protein eL19 isoform X1

    UniProtKB/Swiss-Prot
    P84100
    UniProtKB/TrEMBL
    A0A8I6G776, A6HIP8

  5. XM_039086938.2 → XP_038942866.1  large ribosomal subunit protein eL19 isoform X2

    UniProtKB/TrEMBL
    A0A8I6G776
    Conserved Domains (1) summary
    cd01417
    Location:2 → 165
    Ribosomal_L19e_E; Ribosomal protein L19e, eukaryotic. L19e is found in the large ribosomal subunit of eukaryotes and archaea. L19e is distinct from the ribosomal subunit L19, which is found in prokaryotes. It consists of two small globular domains connected by an ...

  6. XM_039086939.2 → XP_038942867.1  large ribosomal subunit protein eL19 isoform X2

    UniProtKB/TrEMBL
    A0A8I6G776
    Related
    ENSRNOP00000080853.1, ENSRNOT00000100994.2
    Conserved Domains (1) summary
    cd01417
    Location:2 → 165
    Ribosomal_L19e_E; Ribosomal protein L19e, eukaryotic. L19e is found in the large ribosomal subunit of eukaryotes and archaea. L19e is distinct from the ribosomal subunit L19, which is found in prokaryotes. It consists of two small globular domains connected by an ...
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P84100.1 GenPept UniProtKB/Swiss-Prot:P84100

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