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CLPB4 casein lytic proteinase B4 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 817052, updated on 18-Sep-2024

Summary

Official Symbol
CLPB4
Official Full Name
casein lytic proteinase B4
Primary source
TAIR:AT2G25140
Locus tag
AT2G25140
See related
Araport:AT2G25140
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
CASEIN LYTIC PROTEINASE B-M; casein lytic proteinase B4; CLPB-M; F13D4.100; F13D4_100; HEAT SHOCK PROTEIN 98.7; HSP98.7
Summary
Encodes ClpB4, which belongs to the Casein lytic proteinase/heat shock protein 100 (Clp/Hsp100) family. Targeted to the mitochondrion, also referred to as ClpB-m. Transcripts of ClpB4 accumulate dramatically at high temperatures, suggesting that it may be involved in response to heat stress.
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Genomic context

See CLPB4 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
10
Sequence:
Chromosome: 2; NC_003071.7 (10697629..10702203, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ARM repeat superfamily protein Neighboring gene HXXXD-type acyl-transferase family protein Neighboring gene cytochrome P450, family 82, subfamily F, polypeptide 1

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

NM_128071.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in protein refolding IEA
Inferred from Electronic Annotation
more info
 
involved_in response to heat IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
casein lytic proteinase B4
NP_565586.1
  • casein lytic proteinase B4 (CLPB4); FUNCTIONS IN: nucleoside-triphosphatase activity, ATPase activity, nucleotide binding, ATP binding; INVOLVED IN: response to heat; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Clp ATPase, C-terminal (InterPro:IPR019489), ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-2 (InterPro:IPR013093), ATPase, AAA-type, core (InterPro:IPR003959), Chaperonin clpA/B (InterPro:IPR001270), Chaperonin ClpB (InterPro:IPR017730), Chaperonin ClpA/B, conserved site (InterPro:IPR018368), Clp, N-terminal (InterPro:IPR004176); BEST Arabidopsis thaliana protein match is: casein lytic proteinase B3 (TAIR:AT5G15450.1); Has 30488 Blast hits to 27328 proteins in 3166 species: Archae - 421; Bacteria - 19864; Metazoa - 870; Fungi - 613; Plants - 740; Viruses - 7; Other Eukaryotes - 7973 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    10697629..10702203 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_128071.3NP_565586.1  casein lytic proteinase B4 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_565586.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8VYJ7
    UniProtKB/TrEMBL
    A0A178VSB4, A0A654EXJ3
    Conserved Domains (5) summary
    cd00009
    Location:262422
    AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
    TIGR03346
    Location:88949
    chaperone_ClpB; ATP-dependent chaperone ClpB
    pfam02861
    Location:99151
    Clp_N; Clp amino terminal domain, pathogenicity island component
    pfam07724
    Location:683850
    AAA_2; AAA domain (Cdc48 subfamily)
    pfam10431
    Location:857937
    ClpB_D2-small; C-terminal, D2-small domain, of ClpB protein