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UCP5 uncoupling protein 5 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 816783, updated on 18-Sep-2024

Summary

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Official Symbol
UCP5
Official Full Name
uncoupling protein 5
Primary source
TAIR:AT2G22500
Locus tag
AT2G22500
See related
Araport:AT2G22500
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATPUMP5; DIC1; DICARBOXYLATE CARRIER 1; F14M13.10; F14M13_10; PLANT UNCOUPLING MITOCHONDRIAL PROTEIN 5; uncoupling protein 5
Summary
Encodes one of the mitochondrial dicarboxylate carriers (DIC): DIC1 (AT2G22500), DIC2 (AT4G24570), DIC3 (AT5G09470).
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Genomic context

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See UCP5 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
1
Sequence:
Chromosome: 2; NC_003071.7 (9562774..9564850, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene hydroxyproline-rich glycoprotein family protein Neighboring gene uncharacterized protein Neighboring gene Alkaline-phosphatase-like family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The plant energy-dissipating mitochondrial systems: depicting the genomic structure and the expression profiles of the gene families of uncoupling protein and alternative oxidase in monocots and dicots. Borecky J, et al. J Exp Bot, 2006. PMID 16473895
  2. Molecular identification of three Arabidopsis thaliana mitochondrial dicarboxylate carrier isoforms: organ distribution, bacterial expression, reconstitution into liposomes and functional characterization. Palmieri L, et al. Biochem J, 2008 Mar 15. PMID 18039180
  3. Integrative Analysis from the Epigenome to Translatome Uncovers Patterns of Dominant Nuclear Regulation during Transient Stress. Lee TA, et al. Plant Cell, 2019 Nov. PMID 31519798, Free PMC Article
  4. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Miscellaneous features

  • Loc: c9564686-9564579 AT2G22500.uORF1
NM_127816.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables dicarboxylic acid transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables oxidative phosphorylation uncoupler activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within cellular response to hypoxia HEP PubMed 
acts_upstream_of_or_within mitochondrial transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in proton transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
uncoupling protein 5
NP_179836.1
  • uncoupling protein 5 (UCP5); FUNCTIONS IN: binding, dicarboxylic acid transmembrane transporter activity; INVOLVED IN: transport, mitochondrial transport; LOCATED IN: mitochondrion, mitochondrial inner membrane, membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Mitochondrial substrate carrier (InterPro:IPR001993), Mitochondrial brown fat uncoupling protein (InterPro:IPR002030), Mitochondrial substrate/solute carrier (InterPro:IPR018108); BEST Arabidopsis thaliana protein match is: dicarboxylate carrier 2 (TAIR:AT4G24570.1); Has 25222 Blast hits to 13203 proteins in 454 species: Archae - 0; Bacteria - 2; Metazoa - 10525; Fungi - 7328; Plants - 4898; Viruses - 0; Other Eukaryotes - 2469 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    9562774..9564850 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_127816.3 → NP_179836.1  uncoupling protein 5 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_179836.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q0WL82, Q94K32, Q9SJY5
    UniProtKB/TrEMBL
    A0A178W292, A0A5S9X074, Q8LDF6
    Conserved Domains (1) summary
    pfam00153
    Location:216 → 311
    Mito_carr; Mitochondrial carrier protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9SJY5.1

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