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EPF1 epidermal patterning factor 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 816621, updated on 18-Sep-2024

Summary

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Official Symbol
EPF1
Official Full Name
epidermal patterning factor 1
Primary source
TAIR:AT2G20875
Locus tag
AT2G20875
See related
Araport:AT2G20875
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
EPIDERMAL PATTERNING FACTOR 1
Summary
Encodes a secretory peptide EPF1 involved in stomatal development. EPF1 is related to EPF2 which controls asymmetric cell divisions during stomatal devlopment. Its transcript levels change after inducing MUTE expression in a mute background.
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Genomic context

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See EPF1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
2
Sequence:
Chromosome: 2; NC_003071.7 (8982863..8983814, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene lipoic acid synthase 1 Neighboring gene cell wall protein precursor Neighboring gene uncharacterized protein Neighboring gene Integrase-type DNA-binding superfamily protein Neighboring gene photosystem II reaction center PSB29 protein Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The secretory peptide gene EPF1 enforces the stomatal one-cell-spacing rule. Hara K, et al. Genes Dev, 2007 Jul 15. PMID 17639078, Free PMC Article
  2. The signaling peptide EPF2 controls asymmetric cell divisions during stomatal development. Hunt L, et al. Curr Biol, 2009 May 26. PMID 19398336
  3. Autocrine regulation of stomatal differentiation potential by EPF1 and ERECTA-LIKE1 ligand-receptor signaling. Qi X, et al. Elife, 2017 Mar 7. PMID 28266915, Free PMC Article
  4. Evolutionary relationship and structural characterization of the EPF/EPFL gene family. Takata N, et al. PLoS One, 2013. PMID 23755192, Free PMC Article
  5. Differential effects of the peptides Stomagen, EPF1 and EPF2 on activation of MAP kinase MPK6 and the SPCH protein level. Jewaria PK, et al. Plant Cell Physiol, 2013 Aug. PMID 23686240

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Here, the authors report that EPF1 and its primary receptor ERECTA-LIKE1 (ERL1) target MUTE, a transcription factor specifying the proliferation-to-differentiation switch within the stomatal cell lineages. In turn, MUTE directly induces ERL1.
    Title: Autocrine regulation of stomatal differentiation potential by EPF1 and ERECTA-LIKE1 ligand-receptor signaling.
  2. EPF1/EPF2-like proteins form an additional disulfide bond in their loop regions and show greater flexibility in these regions than EPFL9/Stomagen-like peptides.
    Title: Evolutionary relationship and structural characterization of the EPF/EPFL gene family.
  3. EPF1 and EPF2 are able to activate the MAP kinase MPK6, and that both EPF1 and EPF2 are able to decrease the SPCH level, whereas stomagen is able to increase it.
    Title: Differential effects of the peptides Stomagen, EPF1 and EPF2 on activation of MAP kinase MPK6 and the SPCH protein level.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_127657.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within negative regulation of stomatal complex development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within stomatal complex development IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within stomatal complex patterning IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
epidermal patterning factor 1
NP_179684.1
  • EPIDERMAL PATTERNING FACTOR 1 (EPF1); BEST Arabidopsis thaliana protein match is: unknown protein (TAIR:AT1G71866.1); Has 74 Blast hits to 74 proteins in 11 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 74; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    8982863..8983814 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_127657.4 → NP_179684.1  epidermal patterning factor 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_179684.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8S8I4
    UniProtKB/TrEMBL
    A0A178VX97, A0A5S9X054
    Conserved Domains (1) summary
    pfam17181
    Location:53 → 103
    EPF; Epidermal patterning factor proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8S8I4.1

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