OR52P1 olfactory receptor family 52 subfamily P member 1 (gene/pseudogene) [Homo sapiens (human)] - Gene

Summary

Official Symbol: OR52P1provided by HGNC
Official Full Name: olfactory receptor family 52 subfamily P member 1 (gene/pseudogene)provided by HGNC
Primary source: HGNC:HGNC:15232
See related: Ensembl:ENSG00000181109 AllianceGenome:HGNC:15232
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: OR11-66; OR52P1P
Summary: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Annotation information: Note: Genetic polymorphisms result in both protein coding and non-coding alleles of this gene.
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Genomic context

Location:: 11p15.4

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2023_10	current	GRCh38.p14 (GCF_000001405.40)	11	NC_000011.10 (5726502..5727464)
RS_2023_10	current	T2T-CHM13v2.0 (GCF_009914755.1)	11	NC_060935.1 (5784351..5785316)
105.20220307	previous assembly	GRCh37.p13 (GCF_000001405.25)	11	NC_000011.9 (5747732..5748694)

Chromosome 11 - NC_000011.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

stSG611181 (e-PCR)
- UniSTS:449281

stSG611182 (e-PCR)
- UniSTS:449282

ECD03683 (e-PCR)
- UniSTS:284763

ECD04993 (e-PCR)
- UniSTS:286061

ECD05617 (e-PCR)
- UniSTS:286680

REN99358 (e-PCR)
- UniSTS:424155

REN99359 (e-PCR)
- UniSTS:424156

REN99360 (e-PCR)
- UniSTS:424157

REN99361 (e-PCR)
- UniSTS:424158

REN99362 (e-PCR)
- UniSTS:424159

REN99363 (e-PCR)
- UniSTS:424160

REN99364 (e-PCR)
- UniSTS:424161

REN99365 (e-PCR)
- UniSTS:424162

REN99366 (e-PCR)
- UniSTS:424163

REN99367 (e-PCR)
- UniSTS:424164

REN99368 (e-PCR)
- UniSTS:424165

REN99369 (e-PCR)
- UniSTS:424166

REN99370 (e-PCR)
- UniSTS:424167

ECD04339 (e-PCR)
- UniSTS:285416

REN99371 (e-PCR)
- UniSTS:424168

REN99372 (e-PCR)
- UniSTS:424169

Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info
enables olfactory receptor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in detection of chemical stimulus involved in sensory perception of smell	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: olfactory receptor 52P1

Names: Olfactory receptor 52P1; olfactory receptor OR11-66 pseudogene; olfactory receptor family 52 subfamily P member 1 pseudogene; putative olfactory receptor 52P1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001395916.2 → NP_001382845.2 olfactory receptor 52P1

Status: VALIDATED

Source sequence(s)

BK004746

UniProtKB/Swiss-Prot

Q8NH57

Conserved Domains (1) summary

cd15953
Location:27 → 301

7tmA_OR52P-like; olfactory receptor subfamily 52P and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RNA

NR_172915.1 RNA Sequence

Status: VALIDATED

Source sequence(s)

AC109341

Related

ENST00000438474.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

NC_000011.10 Reference GRCh38.p14 Primary Assembly

Range

5726502..5727464

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

NC_060935.1 Alternate T2T-CHM13v2.0

Range

5784351..5785316

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NG_004220.3: Suppressed sequence

Description

NG_004220.3: This RefSeq was removed because it is now thought that this gene does encode a protein in some individuals.