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chmp2a charged multivesicular body protein 2A [ Danio rerio (zebrafish) ]

Gene ID: 798901, updated on 12-Sep-2024

Summary

Official Symbol
chmp2aprovided by ZNC
Official Full Name
charged multivesicular body protein 2Aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2922
See related
Ensembl:ENSDARG00000053979 AllianceGenome:ZFIN:ZDB-GENE-040426-2922
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
bc2; fj10d05; zgc:55361; wu:fi18h03; wu:fj10d05
Summary
Predicted to be involved in several processes, including endosome transport via multivesicular body sorting pathway; exit from mitosis; and late endosome to vacuole transport. Predicted to act upstream of or within vacuolar transport. Predicted to be located in nuclear envelope. Predicted to be part of ESCRT III complex. Predicted to be active in multivesicular body. Orthologous to human CHMP2A (charged multivesicular body protein 2A). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See chmp2a in Genome Data Viewer
Location:
chromosome: 12
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (27027314..27031031, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (26935954..26939671, complement)

Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137496819 Neighboring gene zinc finger protein 438 Neighboring gene MSL complex subunit 1b Neighboring gene fibrosin Neighboring gene Snf2-related CREBBP activator protein

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Markers

Clone Names

  • MGC55361, MGC174106

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in endosome transport via multivesicular body sorting pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in exit from mitosis ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in late endosome to vacuole transport IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in nuclear membrane reassembly ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in protein transport IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within vacuolar transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of ESCRT III complex IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in endosome IEA
Inferred from Electronic Annotation
more info
 
located_in late endosome membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in multivesicular body IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nuclear envelope ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
charged multivesicular body protein 2a
Names
chromatin modifying protein 2A
chromatin-modifying protein 2a
putative breast adenocarcinoma marker

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_213517.1NP_998682.1  charged multivesicular body protein 2a

    See identical proteins and their annotated locations for NP_998682.1

    Status: PROVISIONAL

    Source sequence(s)
    BC045320
    UniProtKB/Swiss-Prot
    Q7ZW25
    Related
    ENSDARP00000070582.4, ENSDART00000076103.5
    Conserved Domains (1) summary
    pfam03357
    Location:17185
    Snf7; Snf7

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007123.7 Reference GRCz11 Primary Assembly

    Range
    27027314..27031031 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)