cd79a CD79a molecule, immunoglobulin-associated alpha [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: cd79aprovided by ZNC
Official Full Name: CD79a molecule, immunoglobulin-associated alphaprovided by ZNC
Primary source: ZFIN:ZDB-GENE-100922-201
See related: Ensembl:ENSDARG00000037473 AllianceGenome:ZFIN:ZDB-GENE-100922-201
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: si:ch211-64k10.2
Summary: Predicted to be involved in B cell differentiation and B cell receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be part of B cell receptor complex. Predicted to be active in external side of plasma membrane. Is expressed in head kidney; intestine; kidney; and spleen. Human ortholog(s) of this gene implicated in agammaglobulinemia 3. Orthologous to human CD79A (CD79a molecule). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 16

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	16	NC_007127.7 (26132680..26140768, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	16	NC_007127.6 (26259238..26267326, complement)

Chromosome 16 - NC_007127.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

this study confirmed a conserved role for CD79 in B cell development and differentiation, without the requirement of a pre-B cell stage in zebrafish
Title: Zebrafish B Cell Development without a Pre-B Cell Stage, Revealed by CD79 Fluorescence Reporter Transgenes.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
involved_in B cell differentiation	IBA Inferred from Biological aspect of Ancestor more info
involved_in B cell receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within B cell receptor signaling pathway	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of B cell receptor complex	IBA Inferred from Biological aspect of Ancestor more info
part_of B cell receptor complex	IEA Inferred from Electronic Annotation more info
is_active_in external side of plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: B-cell antigen receptor complex-associated protein alpha chain

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001326470.1 → NP_001313399.1 B-cell antigen receptor complex-associated protein alpha chain precursor

Status: VALIDATED

Source sequence(s)

BX571738

UniProtKB/TrEMBL

A0A8M1P8N4

Related

ENSDARP00000123803.1, ENSDART00000143960.2

Conserved Domains (2) summary

cd00096
Location:40 → 118

Ig; Immunoglobulin domain

smart00410
Location:30 → 127

IG_like; Immunoglobulin like