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eogt EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase [ Danio rerio (zebrafish) ]

Gene ID: 798087, updated on 25-Apr-2024

Summary

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Official Symbol
eogtprovided by ZNC
Official Full Name
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferaseprovided by ZNC
Primary source
ZFIN:ZDB-GENE-120813-8
See related
Ensembl:ENSDARG00000022853 AllianceGenome:ZFIN:ZDB-GENE-120813-8
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
c3orf64
Summary
Predicted to enable protein N-acetylglucosaminyltransferase activity. Predicted to be involved in protein O-GlcNAcylation via threonine. Predicted to be active in endoplasmic reticulum lumen. Human ortholog(s) of this gene implicated in Adams-Oliver syndrome. Orthologous to human EOGT (EGF domain specific O-linked N-acetylglucosamine transferase). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
human mouse all
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Genomic context

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See eogt in Genome Data Viewer
Location:
chromosome: 11
Exon count:
16
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (17725643..17755441, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (17591313..17620810, complement)

Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 19 member A1, C-C motif chemokine like Neighboring gene TAFA chemokine like family member 4b Neighboring gene TATA element modulatory factor 1 Neighboring gene ubiquitin-like modifier activating enzyme 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Evolution of JAK-STAT pathway components: mechanisms and role in immune system development. Liongue C, et al. PLoS One, 2012. PMID 22412924, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein O-acetylglucosaminyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables protein O-acetylglucosaminyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein O-GlcNAcylation via threonine IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in endoplasmic reticulum lumen IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
EGF domain-specific O-linked N-acetylglucosamine transferase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007122.7 Reference GRCz11 Primary Assembly

    Range
    17725643..17755441 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021479774.1 → XP_021335449.1  EGF domain-specific O-linked N-acetylglucosamine transferase isoform X2

    UniProtKB/TrEMBL
    A0A8M9QDI0
    Conserved Domains (1) summary
    pfam04577
    Location:237 → 459
    DUF563; Protein of unknown function (DUF563)

  2. XM_021479773.1 → XP_021335448.1  EGF domain-specific O-linked N-acetylglucosamine transferase isoform X1

    UniProtKB/TrEMBL
    A0A8M9Q7L1, X1WGG5
    Related
    ENSDARP00000129320.2, ENSDART00000154627.3
    Conserved Domains (1) summary
    pfam04577
    Location:237 → 460
    DUF563; Protein of unknown function (DUF563)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394813.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    74618..114577 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005155821.4 → XP_005155878.2  EGF domain-specific O-linked N-acetylglucosamine transferase isoform X2

    UniProtKB/TrEMBL
    A0A8M2B2I5
    Conserved Domains (1) summary
    pfam04577
    Location:237 → 459
    DUF563; Protein of unknown function (DUF563)

  2. XM_005155820.4 → XP_005155877.2  EGF domain-specific O-linked N-acetylglucosamine transferase isoform X1

    UniProtKB/TrEMBL
    A0A8M2B2Q0
    Conserved Domains (1) summary
    pfam04577
    Location:237 → 460
    DUF563; Protein of unknown function (DUF563)
Nucleotide Protein Strain
Heading Accession and Version

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