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errfi1a ERBB receptor feedback inhibitor 1a [ Danio rerio (zebrafish) ]

Gene ID: 798009, updated on 2-Nov-2024

Summary

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Official Symbol
errfi1aprovided by ZNC
Official Full Name
ERBB receptor feedback inhibitor 1aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-6256
See related
Ensembl:ENSDARG00000104039 AllianceGenome:ZFIN:ZDB-GENE-030131-6256
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
errfi1; wu:fd60d02; wu:fi40f02; zgc:162129
Summary
Predicted to be involved in negative regulation of epidermal growth factor receptor signaling pathway and regulation of keratinocyte differentiation. Orthologous to human ERRFI1 (ERBB receptor feedback inhibitor 1). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See errfi1a in Genome Data Viewer
Location:
chromosome: 11
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (40831633..40844026)
105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (40567488..40579881)

Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene taste receptor, type 1, member 3 Neighboring gene uncharacterized LOC137496731 Neighboring gene uncharacterized LOC101882681 Neighboring gene uncharacterized LOC110440109 Neighboring gene uncharacterized LOC137496732

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. DNA Methylation of T1R1 Gene in the Vegetarian Adaptation of Grass Carp Ctenopharyngodon idella. Cai W, et al. Sci Rep, 2018 May 2. PMID 29720695, Free PMC Article
  2. Transcriptome analysis of Traf6 function in the innate immune response of zebrafish embryos. Stockhammer OW, et al. Mol Immunol, 2010 Nov-Dec. PMID 20851470
  3. Transcriptomic, proteomic, and metabolomic landscape of positional memory in the caudal fin of zebrafish. Rabinowitz JS, et al. Proc Natl Acad Sci U S A, 2017 Jan 31. PMID 28096348, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC162129

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in negative regulation of epidermal growth factor receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of keratinocyte differentiation IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
ERBB receptor feedback inhibitor 1a
Names
ERBB receptor feedback inhibitor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001083570.1 → NP_001077039.1  ERBB receptor feedback inhibitor 1a

    See identical proteins and their annotated locations for NP_001077039.1

    Status: PROVISIONAL

    Source sequence(s)
    BC133880
    UniProtKB/TrEMBL
    A0A8M1NDU2, A3KNJ9
    Related
    ENSDARP00000130213.1, ENSDART00000160023.3
    Conserved Domains (2) summary
    pfam09027
    Location:12 → 73
    GTPase_binding; GTPase binding
    pfam11555
    Location:324 → 368
    Inhibitor_Mig-6; EGFR receptor inhibitor Mig-6

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007122.7 Reference GRCz11 Primary Assembly

    Range
    40831633..40844026
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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