U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

birc6 baculoviral IAP repeat containing 6 [ Danio rerio (zebrafish) ]

Gene ID: 796547, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
birc6provided by ZNC
Official Full Name
baculoviral IAP repeat containing 6provided by ZNC
Primary source
ZFIN:ZDB-GENE-091202-7
See related
Ensembl:ENSDARG00000074166 AllianceGenome:ZFIN:ZDB-GENE-091202-7
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in negative regulation of apoptotic process. Predicted to act upstream of or within apoptotic process; chromosome segregation; and regulation of cytokinesis. Predicted to be located in chromosome, centromeric region. Predicted to be active in nucleus and trans-Golgi network. Orthologous to human BIRC6 (baculoviral IAP repeat containing 6). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See birc6 in Genome Data Viewer
Location:
chromosome: 17
Exon count:
74
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (22587388..22741618)
105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (22567521..22721790)

Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene exonuclease 1 Neighboring gene Yip1 domain family, member 4 Neighboring gene birc6 antisense RNA 2 Neighboring gene tetratricopeptide repeat domain 27 Neighboring gene microRNA 456 Neighboring gene latent transforming growth factor beta binding protein 1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. CD44a functions as a regulator of p53 signaling, apoptosis and autophagy in the antibacterial immune response. Cao L, et al. Commun Biol, 2022 Aug 30. PMID 36042265, Free PMC Article
  2. Reverse genetic screening reveals poor correlation between morpholino-induced and mutant phenotypes in zebrafish. Kok FO, et al. Dev Cell, 2015 Jan 12. PMID 25533206, Free PMC Article
  3. Transcriptome comparison reveals a genetic network regulating the lower temperature limit in fish. Hu P, et al. Sci Rep, 2016 Jun 30. PMID 27356472, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ubiquitin conjugating enzyme activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ubiquitin-protein transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within apoptotic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within chromosome segregation IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of apoptotic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within regulation of cytokinesis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chromosome, centromeric region IEA
Inferred from Electronic Annotation
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in trans-Golgi network IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
baculoviral IAP repeat-containing protein 6
XP_009291311.1
XP_009291312.1
XP_009291313.1
XP_009291314.1
XP_009291315.1
XP_009291316.1
XP_009291317.1
XP_021328806.1
XP_021328807.1
XP_021328809.1
XP_021328810.1
XP_021328811.1
XP_021328812.1
XP_021328813.1
XP_021330033.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007128.7 Reference GRCz11 Primary Assembly

    Range
    22587388..22741618
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009293036.4 → XP_009291311.1  baculoviral IAP repeat-containing protein 6 isoform X1

    UniProtKB/TrEMBL
    A0A8M3AJT6, X1WF03
    Related
    ENSDARP00000128806.1, ENSDART00000157328.3
    Conserved Domains (4) summary
    COG3122
    Location:2200 → 2311
    YaiL; Uncharacterized conserved protein YaiL, DUF2058 family [Function unknown]
    cd00195
    Location:4667 → 4805
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    pfam00653
    Location:248 → 318
    BIR; Inhibitor of Apoptosis domain
    pfam12356
    Location:3501 → 3664
    DUF3643; Protein of unknown function (DUF3643)

  2. XM_009293039.4 → XP_009291314.1  baculoviral IAP repeat-containing protein 6 isoform X4

    UniProtKB/TrEMBL
    A0A8M3AIY4
    Conserved Domains (4) summary
    COG3122
    Location:2200 → 2311
    YaiL; Uncharacterized conserved protein YaiL, DUF2058 family [Function unknown]
    cd00195
    Location:4666 → 4804
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    pfam00653
    Location:248 → 318
    BIR; Inhibitor of Apoptosis domain
    pfam12356
    Location:3500 → 3663
    DUF3643; Protein of unknown function (DUF3643)

  3. XM_009293041.4 → XP_009291316.1  baculoviral IAP repeat-containing protein 6 isoform X6

    UniProtKB/TrEMBL
    A0A8M3AJT9
    Conserved Domains (4) summary
    COG3122
    Location:2200 → 2311
    YaiL; Uncharacterized conserved protein YaiL, DUF2058 family [Function unknown]
    cd00195
    Location:4657 → 4795
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    pfam00653
    Location:248 → 318
    BIR; Inhibitor of Apoptosis domain
    pfam12356
    Location:3491 → 3654
    DUF3643; Protein of unknown function (DUF3643)

  4. XM_009293037.4 → XP_009291312.1  baculoviral IAP repeat-containing protein 6 isoform X2

    UniProtKB/TrEMBL
    A0A8M3AU88
    Conserved Domains (3) summary
    cd00195
    Location:4666 → 4804
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    pfam00653
    Location:248 → 318
    BIR; Inhibitor of Apoptosis domain
    pfam12356
    Location:3500 → 3663
    DUF3643; Protein of unknown function (DUF3643)

  5. XM_009293038.4 → XP_009291313.1  baculoviral IAP repeat-containing protein 6 isoform X3

    UniProtKB/TrEMBL
    A0A8M3ARC4
    Conserved Domains (4) summary
    COG3122
    Location:2199 → 2310
    YaiL; Uncharacterized conserved protein YaiL, DUF2058 family [Function unknown]
    cd00195
    Location:4666 → 4804
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    pfam00653
    Location:248 → 318
    BIR; Inhibitor of Apoptosis domain
    pfam12356
    Location:3500 → 3663
    DUF3643; Protein of unknown function (DUF3643)

  6. XM_009293040.4 → XP_009291315.1  baculoviral IAP repeat-containing protein 6 isoform X5

    UniProtKB/TrEMBL
    A0A8M3B2D6
    Conserved Domains (4) summary
    COG3122
    Location:2196 → 2307
    YaiL; Uncharacterized conserved protein YaiL, DUF2058 family [Function unknown]
    cd00195
    Location:4663 → 4801
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    pfam00653
    Location:248 → 318
    BIR; Inhibitor of Apoptosis domain
    pfam12356
    Location:3497 → 3660
    DUF3643; Protein of unknown function (DUF3643)

  7. XM_009293042.4 → XP_009291317.1  baculoviral IAP repeat-containing protein 6 isoform X7

    UniProtKB/TrEMBL
    A0A8M3AU93
    Conserved Domains (4) summary
    COG3122
    Location:2196 → 2307
    YaiL; Uncharacterized conserved protein YaiL, DUF2058 family [Function unknown]
    cd00195
    Location:4653 → 4791
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    pfam00653
    Location:248 → 318
    BIR; Inhibitor of Apoptosis domain
    pfam12356
    Location:3487 → 3650
    DUF3643; Protein of unknown function (DUF3643)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394987.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    956..124803
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021473131.1 → XP_021328806.1  baculoviral IAP repeat-containing protein 6 isoform X8

    UniProtKB/TrEMBL
    A0A8M9Q2B0
    Conserved Domains (3) summary
    cd00022
    Location:246 → 319
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
    cd00195
    Location:4669 → 4807
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    pfam12356
    Location:3501 → 3664
    BIRC6; Baculoviral IAP repeat-containing protein 6

  2. XM_021473138.1 → XP_021328813.1  baculoviral IAP repeat-containing protein 6 isoform X14

    UniProtKB/TrEMBL
    A0A8M9PP49
    Conserved Domains (3) summary
    cd00022
    Location:246 → 319
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
    cd00195
    Location:4639 → 4777
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    pfam12356
    Location:3471 → 3634
    BIRC6; Baculoviral IAP repeat-containing protein 6

  3. XM_021473136.1 → XP_021328811.1  baculoviral IAP repeat-containing protein 6 isoform X12

    UniProtKB/TrEMBL
    A0A8M9Q2C3
    Conserved Domains (3) summary
    cd00022
    Location:246 → 319
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
    cd00195
    Location:4659 → 4797
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    pfam12356
    Location:3491 → 3654
    BIRC6; Baculoviral IAP repeat-containing protein 6

  4. XM_021473132.1 → XP_021328807.1  baculoviral IAP repeat-containing protein 6 isoform X9

    UniProtKB/TrEMBL
    A0A8M9PCN7
    Conserved Domains (3) summary
    cd00022
    Location:246 → 319
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
    cd00195
    Location:4668 → 4806
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    pfam12356
    Location:3500 → 3663
    BIRC6; Baculoviral IAP repeat-containing protein 6

  5. XM_021473134.1 → XP_021328809.1  baculoviral IAP repeat-containing protein 6 isoform X10

    UniProtKB/TrEMBL
    A0A8M9PVD8
    Conserved Domains (3) summary
    cd00022
    Location:246 → 319
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
    cd00195
    Location:4668 → 4806
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    pfam12356
    Location:3500 → 3663
    BIRC6; Baculoviral IAP repeat-containing protein 6

  6. XM_021473135.1 → XP_021328810.1  baculoviral IAP repeat-containing protein 6 isoform X11

    UniProtKB/TrEMBL
    A0A8M9Q6H7
    Conserved Domains (3) summary
    cd00022
    Location:246 → 319
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
    cd00195
    Location:4665 → 4803
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    pfam12356
    Location:3497 → 3660
    BIRC6; Baculoviral IAP repeat-containing protein 6

  7. XM_021473137.1 → XP_021328812.1  baculoviral IAP repeat-containing protein 6 isoform X13

    UniProtKB/TrEMBL
    A0A8M9PCP7
    Conserved Domains (3) summary
    cd00022
    Location:246 → 319
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
    cd00195
    Location:4655 → 4793
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    pfam12356
    Location:3487 → 3650
    BIRC6; Baculoviral IAP repeat-containing protein 6

Reference GRCz11 ALT_DRER_TU_2

Genomic

  1. NW_018395328.1 Reference GRCz11 ALT_DRER_TU_2

    Range
    304318..338418
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021474358.2 → XP_021330033.1  baculoviral IAP repeat-containing protein 6 isoform X15

    UniProtKB/TrEMBL
    A0A8M9PSN1
    Conserved Domains (1) summary
    cd00022
    Location:246 → 319
    BIR; Baculoviral inhibition of apoptosis protein repeat domain; Found in inhibitors of apoptosis proteins (IAPs) and other proteins. In higher eukaryotes, BIR domains inhibit apoptosis by acting as direct inhibitors of the caspase family of protease enzymes. ...
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools