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znf385c zinc finger protein 385C [ Danio rerio (zebrafish) ]

Gene ID: 793202, updated on 2-Nov-2024

Summary

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Official Symbol
znf385cprovided by ZNC
Official Full Name
zinc finger protein 385Cprovided by ZNC
Primary source
ZFIN:ZDB-GENE-091112-1
See related
Ensembl:ENSDARG00000058154 AllianceGenome:ZFIN:ZDB-GENE-091112-1
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:dkey-26l17.1
Summary
Predicted to enable nucleic acid binding activity and zinc ion binding activity. Located in nucleus. Is expressed in Purkinje cell. Orthologous to human ZNF385C (zinc finger protein 385C). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See znf385c in Genome Data Viewer
Location:
chromosome: 3
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (17744313..17863294)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (17594545..17713559)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene K(lysine) acetyltransferase 2A Neighboring gene DEXH (Asp-Glu-X-His) box polypeptide 58 Neighboring gene NFKB inhibitor interacting Ras-like 2 Neighboring gene DnaJ (Hsp40) homolog, subfamily C, member 7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Znf385C mediates a novel p53-dependent transcriptional switch to control timing of facial bone formation. Hochgreb-Hägele T, et al. Dev Biol, 2015 Apr 1. PMID 25636963
  2. A versatile gene trap to visualize and interrogate the function of the vertebrate proteome. Trinh le A, et al. Genes Dev, 2011 Nov 1. PMID 22056673, Free PMC Article
  3. Analysis of protein expression in developmental toxicity induced by MeHg in zebrafish. Cuello S, et al. Analyst, 2012 Nov 21. PMID 23014190
  4. Molecular analyses of zebrafish V0v spinal interneurons and identification of transcriptional regulators downstream of Evx1 and Evx2 in these cells. England SJ, et al. Neural Dev, 2023 Nov 28. PMID 38017520, Free PMC Article
  5. Gene expression profiling of granule cells and Purkinje cells in the zebrafish cerebellum. Takeuchi M, et al. J Comp Neurol, 2017 May 1. PMID 27615194

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
zinc finger protein 385C

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    17744313..17863294
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001921873.7 → XP_001921908.1  zinc finger protein 385C isoform X1

    UniProtKB/TrEMBL
    A0A8M1QV45
    Conserved Domains (3) summary
    smart00451
    Location:78 → 105
    ZnF_U1; U1-like zinc finger
    sd00020
    Location:240 → 262
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12171
    Location:304 → 329
    zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding

  2. XM_005163883.5 → XP_005163940.1  zinc finger protein 385C isoform X2

    UniProtKB/TrEMBL
    A0A8M2BBE7, E9QJ33
    Related
    ENSDARP00000113568.2, ENSDART00000132622.3
    Conserved Domains (3) summary
    smart00451
    Location:78 → 105
    ZnF_U1; U1-like zinc finger
    sd00020
    Location:240 → 262
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12171
    Location:304 → 329
    zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding

  3. XM_005163884.5 → XP_005163941.1  zinc finger protein 385C isoform X3

    UniProtKB/TrEMBL
    A0A8M2BB30
    Conserved Domains (3) summary
    smart00451
    Location:224 → 249
    ZnF_U1; U1-like zinc finger
    sd00020
    Location:226 → 248
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam12171
    Location:290 → 315
    zf-C2H2_jaz; Zinc-finger double-stranded RNA-binding
Nucleotide Protein Strain
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