got1l1 glutamic-oxaloacetic transaminase 1 like 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: got1l1provided by ZNC
Official Full Name: glutamic-oxaloacetic transaminase 1 like 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-060929-556
See related: Ensembl:ENSDARG00000053644 AllianceGenome:ZFIN:ZDB-GENE-060929-556
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: got1; wu:fj01g02; zgc:152691
Summary: Predicted to enable L-aspartate:2-oxoglutarate aminotransferase activity. Predicted to be involved in aspartate biosynthetic process. Predicted to act upstream of or within biosynthetic process and cellular amino acid metabolic process. Predicted to be active in cytosol. Orthologous to human GOT1L1 (glutamic-oxaloacetic transaminase 1 like 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: all
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Genomic context

Location:: chromosome: 8

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	8	NC_007119.7 (37755099..37772150)
105	previous assembly	GRCz10 (GCF_000002035.5)	8	NC_007119.6 (37722665..37739716)

Chromosome 8 - NC_007119.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fj08h09.x1 (e-PCR)
- UniSTS:198472

fj01g02.x1 (e-PCR)
- UniSTS:198255

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables L-aspartate:2-oxoglutarate aminotransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables L-aspartate:2-oxoglutarate aminotransferase activity	IEA Inferred from Electronic Annotation more info
enables pyridoxal phosphate binding	IEA Inferred from Electronic Annotation more info
enables transaminase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within amino acid metabolic process	IEA Inferred from Electronic Annotation more info
involved_in aspartate biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within biosynthetic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: putative aspartate aminotransferase, cytoplasmic 2

Names: glutamic-oxaloacetic transaminase 1, soluble

NP_001116776.1

EC 2.6.1.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001123304.1 → NP_001116776.1 putative aspartate aminotransferase, cytoplasmic 2

Status: PROVISIONAL

Source sequence(s)

CR749761

UniProtKB/TrEMBL

A0A8M1NIL9, B0UYT6

Related

ENSDARP00000070190.5, ENSDART00000075708.7

Conserved Domains (2) summary

pfam00155
Location:43 → 415

Aminotran_1_2; Aminotransferase class I and II

cl18945
Location:31 → 419

AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...