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b3gnt5b UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5b [ Danio rerio (zebrafish) ]

Gene ID: 791470, updated on 12-Sep-2024

Summary

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Official Symbol
b3gnt5bprovided by ZNC
Official Full Name
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-041010-166
See related
Ensembl:ENSDARG00000004396 AllianceGenome:ZFIN:ZDB-GENE-041010-166
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:101733
Summary
Predicted to enable beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity. Predicted to be involved in brain development. Predicted to be located in Golgi apparatus and membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi membrane. Is expressed in prechordal plate. Orthologous to human B3GNT5 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See b3gnt5b in Genome Data Viewer
Location:
chromosome: 2
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (7749394..7757273, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (7951389..7959268, complement)

Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA81 Neighboring gene small nucleolar RNA SNORD2 Neighboring gene eukaryotic translation initiation factor 4A2 Neighboring gene TBL1X/Y related 1b Neighboring gene potassium large conductance calcium-activated channel, subfamily M, beta member 2a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Gene duplication of C-type natriuretic peptide-4 (CNP4) in teleost lineage elicits subfunctionalization of ancestral CNP. Katayama Y, et al. Cell Tissue Res, 2022 May. PMID 35171324
  2. Single-cell reconstruction of developmental trajectories during zebrafish embryogenesis. Farrell JA, et al. Science, 2018 Jun 1. PMID 29700225, Free PMC Article
  3. Phylogenetic and developmental analyses indicate complex functions of calcium-activated potassium channels in zebrafish embryonic development. Silic MR, et al. Dev Dyn, 2021 Oct. PMID 33728688, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC101733

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables hexosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in protein O-linked glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase B
Names
BGnT-5B
UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5B
beta-1,3-Gn-T5B
beta-1,3-N-acetylglucosaminyltransferase 5B
beta3Gn-T5B
lactotriaosylceramide synthase B
lc(3)Cer synthase B
lc3 synthase B
NP_001093515.1
XP_068068985.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001100045.1 → NP_001093515.1  lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase B

    Status: PROVISIONAL

    Source sequence(s)
    CT027646
    UniProtKB/Swiss-Prot
    Q5XJP0
    UniProtKB/TrEMBL
    A0A8M1NDQ2, A5WVT9
    Related
    ENSDARP00000123385.1, ENSDART00000136074.2
    Conserved Domains (1) summary
    cl21608
    Location:119 → 317
    Galactosyl_T; Galactosyltransferase

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007113.7 Reference GRCz11 Primary Assembly

    Range
    7749394..7757273 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068212884.1 → XP_068068985.1  lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase B isoform X1

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5XJP0.1 GenPept UniProtKB/Swiss-Prot:Q5XJP0

Gene LinkOut

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