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MIR545 microRNA mir-545 [ Bos taurus (domestic cattle) ]

Gene ID: 791022, updated on 4-Oct-2024

Summary

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Gene symbol
MIR545
Gene description
microRNA mir-545
See related
Ensembl:ENSBTAG00000030019 miRBase:MI0005023
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
MIRN545; bta-mir-545
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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Genomic context

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See MIR545 in Genome Data Viewer
Location:
chromosome: X
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) X NC_037357.1 (76853198..76853303)

Chromosome X - NC_037357.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC104970537 Neighboring gene zinc finger CCHC-type containing 13 Neighboring gene microRNA mir-374a Neighboring gene microRNA mir-374c Neighboring gene microRNA mir-374b Neighboring gene microRNA mir-421

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037357.1 Chromosome X Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification and expression profiling of microRNAs during bovine oocyte maturation using heterologous approach. Tesfaye D, et al. Mol Reprod Dev, 2009 Jul. PMID 19170227
  2. Discovery and profiling of bovine microRNAs from immune-related and embryonic tissues. Coutinho LL, et al. Physiol Genomics, 2007 Mar 14. PMID 17105755
  3. miRBase: microRNA sequences, targets and gene nomenclature. Griffiths-Jones S, et al. Nucleic Acids Res, 2006 Jan 1. PMID 16381832, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Other Names

  • microRNA 545

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_031358.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    NKLS02000030
    Related
    ENSBTAT00000042398.2

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037357.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    76853198..76853303
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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