IGF2R insulin like growth factor 2 receptor [Ornithorhynchus anatinus (platypus)] - Gene

Summary

Gene symbol: IGF2R
Gene description: insulin like growth factor 2 receptor
See related: Ensembl:ENSOANG00000007296
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Ornithorhynchus anatinus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus
Also known as: M6P/IGF2R
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 48

Annotation release	Status	Assembly	Chr	Location
105	current	mOrnAna1.pri.v4 (GCF_004115215.2)	2	NC_041729.1 (64404043..64562775, complement)

Chromosome 2 - NC_041729.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_041729.1 Chromosome 2 Reference mOrnAna1.pri.v4 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables D-mannose binding	IEA Inferred from Electronic Annotation more info	PubMed
enables insulin-like growth factor binding	IEA Inferred from Electronic Annotation more info	PubMed
enables signaling receptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in lysosomal transport	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in late endosome	IEA Inferred from Electronic Annotation more info	PubMed
located_in plasma membrane	IEA Inferred from Electronic Annotation more info	PubMed
located_in trans-Golgi network	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: cation-independent mannose-6-phosphate receptor

Names: mannose 6-phosphate/insulin-like growth factor 2 receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001127613.1 → NP_001121085.1 cation-independent mannose-6-phosphate receptor precursor

See identical proteins and their annotated locations for NP_001121085.1

Status: PROVISIONAL

Source sequence(s)

AF151172

UniProtKB/TrEMBL

F6XWX1, Q9N1T0

Related

ENSOANP00000011617.2, ENSOANT00000011619.3

Conserved Domains (2) summary

smart00059
Location:1888 → 1933

FN2; Fibronectin type 2 domain

pfam00878
Location:1021 → 1167

CIMR; Cation-independent mannose-6-phosphate receptor repeat