Tas2r118 taste receptor, type 2, member 118 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Tas2r118provided by RGD
Official Full Name: taste receptor, type 2, member 118provided by RGD
Primary source: RGD:620735
See related: EnsemblRapid:ENSRNOG00000021799 AllianceGenome:RGD:620735
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: T2R3; Tas2r16
Summary: Predicted to enable bitter taste receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of bitter taste. Predicted to be located in endoplasmic reticulum; external side of plasma membrane; and trans-Golgi network. Predicted to be active in membrane. Human ortholog(s) of this gene implicated in alcohol dependence. Orthologous to human TAS2R16 (taste 2 receptor member 16). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: 4q22

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	4	NC_086022.1 (53414815..53415714, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	4	NC_051339.1 (52449208..52450107, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	4	NC_005103.4 (51002218..51003117, complement)

Chromosome 4 - NC_086022.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info
enables bitter taste receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables bitter taste receptor activity	ISO Inferred from Sequence Orthology more info
enables taste receptor activity	TAS Traceable Author Statement more info	PubMed

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in detection of chemical stimulus involved in sensory perception of bitter taste	IBA Inferred from Biological aspect of Ancestor more info
involved_in detection of chemical stimulus involved in sensory perception of bitter taste	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	ISO Inferred from Sequence Orthology more info
located_in external side of plasma membrane	ISO Inferred from Sequence Orthology more info
is_active_in membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in trans-Golgi network	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: taste receptor type 2 member 16

Names: T2R16; T2R18

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_023994.1 → NP_076484.1 taste receptor type 2 member 16

See identical proteins and their annotated locations for NP_076484.1

Status: PROVISIONAL

Source sequence(s)

AF227141

UniProtKB/Swiss-Prot

Q9JKU0

UniProtKB/TrEMBL

A6IE78

Related

ENSRNOP00000031530.1, ENSRNOT00000034936.3

Conserved Domains (2) summary

cd14964
Location:9 → 34

7tm_GPCRs; TM helix 1 [structural motif]

cl28897
Location:8 → 290

7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily