U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

mrtfb myocardin related transcription factor B [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 780107, updated on 4-Nov-2024

Summary

Official Symbol
mrtfbprovided by Xenbase
Official Full Name
myocardin related transcription factor Bprovided by Xenbase
Primary source
Xenbase:XB-GENE-487634
See related
Ensembl:ENSXETG00000010993 AllianceGenome:Xenbase:XB-GENE-487634
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
mkl2; MRTF-B; npd001
Summary
Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II. Orthologous to human MRTFB (myocardin related transcription factor B). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See mrtfb in Genome Data Viewer
Location:
chromosome: 9
Exon count:
20
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 9 NC_030685.2 (35558291..35746044)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 9 NC_030685.1 (32383183..32574344, complement)

Chromosome 9 - NC_030685.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC116407690 Neighboring gene excision repair cross-complementation group 4 Neighboring gene transfer RNA threonine (anticodon CGU) Neighboring gene uncharacterized LOC116407672 Neighboring gene microRNA mir-193

Genomic regions, transcripts, and products

General protein information

Preferred Names
myocardin-related transcription factor B
Names
MKL/myocardin-like 2
MKL1/myocardin like 2

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001079182.1NP_001072650.1  myocardin-related transcription factor B

    See identical proteins and their annotated locations for NP_001072650.1

    Status: PROVISIONAL

    Source sequence(s)
    BC123933
    UniProtKB/TrEMBL
    A0A803KHK0, F6UAT7, Q08D56
    Related
    ENSXETP00000024057.4, ENSXETT00000024057.5
    Conserved Domains (4) summary
    smart00707
    Location:3964
    RPEL; Repeat in Drosophila CG10860, human KIAA0680 and C. elegans F26H9.2
    cd00187
    Location:544586
    TOP4c; DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA ...
    pfam02037
    Location:382415
    SAP; SAP domain
    pfam02755
    Location:129149
    RPEL; RPEL repeat

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030685.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    35558291..35746044
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012970561.3XP_012826015.1  myocardin-related transcription factor B isoform X1

    UniProtKB/TrEMBL
    A0A6I8RTA4, A0A6I8SUD3
    Related
    ENSXETP00000085963.1, ENSXETT00000075638.2
    Conserved Domains (5) summary
    PHA03247
    Location:693936
    PHA03247; large tegument protein UL36; Provisional
    pfam02037
    Location:394427
    SAP; SAP domain
    pfam02755
    Location:141163
    RPEL; RPEL repeat
    cl27170
    Location:563602
    DUF460; Protein of unknown function (DUF460)
    cl29414
    Location:5276
    RPEL; RPEL repeat
  2. XM_031892741.1XP_031748601.1  myocardin-related transcription factor B isoform X2

    UniProtKB/TrEMBL
    A0A6I8SUD3, A0A6I8T2P5
    Related
    ENSXETP00000101564.2, ENSXETT00000074228.2
    Conserved Domains (5) summary
    PRK10263
    Location:737879
    PRK10263; DNA translocase FtsK; Provisional
    pfam02037
    Location:394427
    SAP; SAP domain
    pfam02755
    Location:141163
    RPEL; RPEL repeat
    cl27170
    Location:563602
    DUF460; Protein of unknown function (DUF460)
    cl29414
    Location:5276
    RPEL; RPEL repeat
  3. XM_031892742.1XP_031748602.1  myocardin-related transcription factor B isoform X3

    UniProtKB/TrEMBL
    A0A6I8RN18, A0A6I8SUD3
    Related
    ENSXETP00000086540.2, ENSXETT00000094851.2
    Conserved Domains (5) summary
    PHA03247
    Location:639882
    PHA03247; large tegument protein UL36; Provisional
    pfam02037
    Location:340373
    SAP; SAP domain
    pfam02755
    Location:96117
    RPEL; RPEL repeat
    cl27170
    Location:509548
    DUF460; Protein of unknown function (DUF460)
    cl29414
    Location:5276
    RPEL; RPEL repeat
  4. XM_031892740.1XP_031748600.1  myocardin-related transcription factor B isoform X1

    UniProtKB/TrEMBL
    A0A6I8RTA4, A0A6I8SUD3
    Conserved Domains (5) summary
    PHA03247
    Location:693936
    PHA03247; large tegument protein UL36; Provisional
    pfam02037
    Location:394427
    SAP; SAP domain
    pfam02755
    Location:141163
    RPEL; RPEL repeat
    cl27170
    Location:563602
    DUF460; Protein of unknown function (DUF460)
    cl29414
    Location:5276
    RPEL; RPEL repeat
  5. XM_018097150.2XP_017952639.1  myocardin-related transcription factor B isoform X1

    UniProtKB/TrEMBL
    A0A6I8RTA4, A0A6I8SUD3
    Conserved Domains (5) summary
    PHA03247
    Location:693936
    PHA03247; large tegument protein UL36; Provisional
    pfam02037
    Location:394427
    SAP; SAP domain
    pfam02755
    Location:141163
    RPEL; RPEL repeat
    cl27170
    Location:563602
    DUF460; Protein of unknown function (DUF460)
    cl29414
    Location:5276
    RPEL; RPEL repeat