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tkfc triokinase/FMN cyclase [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 779584, updated on 4-Nov-2024

Summary

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Official Symbol
tkfcprovided by Xenbase
Official Full Name
triokinase/FMN cyclaseprovided by Xenbase
Primary source
Xenbase:XB-GENE-990423
See related
Ensembl:ENSXETG00000008822 AllianceGenome:Xenbase:XB-GENE-990423
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
dak
Summary
Predicted to enable ATP binding activity; FAD-AMP lyase (cyclizing) activity; and glycerone kinase activity. Predicted to act upstream of or within glycerol metabolic process and phosphorylation. Orthologous to human TKFC (triokinase and FMN cyclase). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See tkfc in Genome Data Viewer
Location:
chromosome: 4
Exon count:
20
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 4 NC_030680.2 (24016959..24035955, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 4 NC_030680.1 (14653808..14673542, complement)

Chromosome 4 - NC_030680.2Genomic Context describing neighboring genes Neighboring gene Bet1 golgi vesicular membrane trafficking protein like Neighboring gene transmembrane protein 138 Neighboring gene damage-specific DNA binding protein 1 Neighboring gene protein phosphatase 1 regulatory subunit 12A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables FAD-AMP lyase (cyclizing) activity IEA
Inferred from Electronic Annotation
more info
  
enables glycerone kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables phosphotransferase activity, alcohol group as acceptor IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within glycerol metabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within phosphorylation IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
triokinase/FMN cyclase
Names
dihydroxyacetone kinase 2 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030680.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    24016959..24035955 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012962152.3 → XP_012817606.2  triokinase/FMN cyclase isoform X1

    UniProtKB/TrEMBL
    F6VLE3, Q08CW2
    Related
    ENSXETP00000057401.4, ENSXETT00000057401.4
    Conserved Domains (1) summary
    cl29418
    Location:5 → 569
    Dak2; DAK2 domain

  2. XM_012962155.3 → XP_012817609.2  triokinase/FMN cyclase isoform X2

    UniProtKB/TrEMBL
    A0A6I8R6P9, Q08CW2
    Related
    ENSXETP00000080630.2, ENSXETT00000078238.2
    Conserved Domains (1) summary
    cl29418
    Location:2 → 539
    Dak2; DAK2 domain

  3. XM_031900554.1 → XP_031756414.1  triokinase/FMN cyclase isoform X1

    UniProtKB/TrEMBL
    F6VLE3, Q08CW2
    Related
    ENSXETP00000019391.4, ENSXETT00000019391.5
    Conserved Domains (1) summary
    cl29418
    Location:5 → 569
    Dak2; DAK2 domain

  4. XM_018093321.2 → XP_017948810.2  triokinase/FMN cyclase isoform X1

    UniProtKB/TrEMBL
    F6VLE3, Q08CW2
    Conserved Domains (1) summary
    cl29418
    Location:5 → 569
    Dak2; DAK2 domain

  5. XM_002937653.4 → XP_002937699.3  triokinase/FMN cyclase isoform X1

    UniProtKB/TrEMBL
    F6VLE3, Q08CW2
    Related
    ENSXETP00000111748.1, ENSXETT00000115524.1
    Conserved Domains (1) summary
    cl29418
    Location:5 → 569
    Dak2; DAK2 domain
Nucleotide Protein Strain
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