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septin5.S septin 5 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 779425, updated on 4-Nov-2024

Summary

Official Symbol
septin5.S
Official Full Name
septin 5 S homeolog
Primary source
Xenbase:XB-GENE-5829823
Locus tag
XELAEV_18010545mg
See related
EnsemblRapid:ENSXLAG00005010656 AllianceGenome:Xenbase:XB-GENE-5829823
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
sep1; sept1; sept5; sept5.S; sept5in.S
Summary
Predicted to enable GTP binding activity; GTPase activity; and molecular adaptor activity. Predicted to act upstream of or within cytoskeleton-dependent cytokinesis and regulation of exocytosis. Predicted to be located in cell division site; cytoskeleton; and synaptic vesicle. Predicted to be part of septin complex. Is expressed in ectoderm; nervous system; sensory system; urinary system; and vestibuloauditory system. Orthologous to human SEPTIN5 (septin 5). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See septin5.S in Genome Data Viewer
Location:
chromosome: 1S
Exon count:
15
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 1S NC_054372.1 (143207896..143243212)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 1S NC_030725.1 (127453043..127488605)

Chromosome 1S - NC_054372.1Genomic Context describing neighboring genes Neighboring gene claudin 5 (transmembrane protein deleted in velocardiofacial syndrome) S homeolog Neighboring gene septin 5 gene 2 S homeolog Neighboring gene glycoprotein Ib platelet subunit beta S homeolog Neighboring gene uncharacterized LOC121399486

Genomic regions, transcripts, and products

General gene information

Clone Names

  • MGC86286

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 
enables molecular adaptor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within cytoskeleton-dependent cytokinesis IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within regulation of exocytosis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cell division site IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
located_in microtubule cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
part_of septin complex IEA
Inferred from Electronic Annotation
more info
 
located_in septin ring IEA
Inferred from Electronic Annotation
more info
 
located_in synaptic vesicle IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
septin 5 S homeolog
Names
septin 1
NP_001090512.1
XP_018095612.1
XP_018095614.1
XP_018095620.1
XP_018095626.1
XP_018095634.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001097043.1NP_001090512.1  septin 5 S homeolog

    See identical proteins and their annotated locations for NP_001090512.1

    Status: PROVISIONAL

    Source sequence(s)
    BC080406
    UniProtKB/TrEMBL
    A0A974I1W5, Q0VGX0
    Conserved Domains (2) summary
    COG5019
    Location:23351
    CDC3; Septin family protein [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton]
    pfam00735
    Location:41313
    Septin; Septin

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054372.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    143207896..143243212
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018240123.2XP_018095612.1  septin 5 S homeolog isoform X1

    UniProtKB/TrEMBL
    A0A1L8HQF7, A0A974I1M5
    Related
    ENSXLAP00005031463.1, ENSXLAT00005032233.1
  2. XM_018240125.2XP_018095614.1  septin 5 S homeolog isoform X2

    UniProtKB/TrEMBL
    A0A8J0U378
  3. XM_018240145.2XP_018095634.1  septin 5 S homeolog isoform X5

    UniProtKB/TrEMBL
    A0A8J0U2T1
    Related
    ENSXLAP00005031446.1, ENSXLAT00005032216.1
  4. XM_018240137.2XP_018095626.1  septin 5 S homeolog isoform X4

    UniProtKB/TrEMBL
    A0A8J0U383
    Related
    ENSXLAP00005031433.1, ENSXLAT00005032203.1
  5. XM_018240131.2XP_018095620.1  septin 5 S homeolog isoform X3

    UniProtKB/TrEMBL
    A0A8J0U427
    Related
    ENSXLAP00005031429.1, ENSXLAT00005032199.1