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haghl.S hydroxyacylglutathione hydrolase like S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 779396, updated on 4-Nov-2024

Summary

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Official Symbol
haghl.S
Official Full Name
hydroxyacylglutathione hydrolase like S homeolog
Primary source
Xenbase:XB-GENE-987563
Locus tag
XELAEV_18047776mg
See related
EnsemblRapid:ENSXLAG00005011014 AllianceGenome:Xenbase:XB-GENE-987563
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
haghl
Summary
Predicted to enable hydroxyacylglutathione hydrolase activity and metal ion binding activity. Predicted to act upstream of or within methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione. Orthologous to human HAGHL (hydroxyacylglutathione hydrolase like). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See haghl.S in Genome Data Viewer
Location:
chromosome: 9_10S
Exon count:
9
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10S NC_054388.1 (105313399..105324953)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10S NC_030741.1 (98682088..98693736)

Chromosome 9_10S - NC_054388.1Genomic Context describing neighboring genes Neighboring gene heparan sulfate-glucosamine 3-sulfotransferase 6 S homeolog Neighboring gene hydroxyacylglutathione hydrolase S homeolog Neighboring gene cytosolic iron-sulfur assembly component 3 S homeolog Neighboring gene thyroid hormone down-regulated protein (gene 20) S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC154399

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydroxyacylglutathione hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
hydroxyacylglutathione hydrolase like S homeolog
NP_001090483.1
XP_018093135.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001097014.1 → NP_001090483.1  hydroxyacylglutathione hydrolase like S homeolog

    See identical proteins and their annotated locations for NP_001090483.1

    Status: PROVISIONAL

    Source sequence(s)
    BC123176
    UniProtKB/TrEMBL
    A0A974BVT8, Q0IHF6
    Related
    ENSXLAP00005032406.1, ENSXLAT00005033192.1
    Conserved Domains (3) summary
    PLN02469
    Location:1 → 268
    PLN02469; hydroxyacylglutathione hydrolase
    pfam16123
    Location:186 → 265
    HAGH_C; Hydroxyacylglutathione hydrolase C-terminus
    cd07723
    Location:4 → 185
    hydroxyacylglutathione_hydrolase_MBL-fold; hydroxyacylglutathione hydrolase, MBL-fold metallo-hydrolase domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054388.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    105313399..105324953
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018237646.2 → XP_018093135.1  hydroxyacylglutathione hydrolase like S homeolog isoform X1

    UniProtKB/TrEMBL
    A0A1L8EQW2, A0A974BVQ4, A0A974BVT8
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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