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evl.S Enah/Vasp-like S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 779377, updated on 4-Nov-2024

Summary

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Official Symbol
evl.S
Official Full Name
Enah/Vasp-like S homeolog
Primary source
Xenbase:XB-GENE-17343878
Locus tag
XELAEV_18041204mg
See related
EnsemblRapid:ENSXLAG00005004697 AllianceGenome:Xenbase:XB-GENE-17343878
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
evl; xevl
Summary
Predicted to enable SH3 domain binding activity; actin binding activity; and profilin binding activity. Predicted to act upstream of or within actin polymerization or depolymerization; positive regulation of actin filament polymerization; and protein homotetramerization. Predicted to be located in cell projection; cytoplasm; and stress fiber. Orthologous to human EVL (Enah/Vasp-like). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See evl.S in Genome Data Viewer
Location:
chromosome: 8S
Exon count:
16
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 8S NC_054386.1 (12487861..12581250, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 8S NC_030739.1 (12417229..12510864, complement)

Chromosome 8S - NC_054386.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29 S homeolog Neighboring gene YY1 transcription factor S homeolog Neighboring gene uncharacterized LOC108699780 Neighboring gene echinoderm microtubule-associated protein-like 1 Neighboring gene uncharacterized LOC108699782

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Regulation of otic vesicle and hair cell stereocilia morphogenesis by Ena/VASP-like (Evl) in Xenopus. Wanner SJ, et al. J Cell Sci, 2007 Aug 1. PMID 17635997
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC80676

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables SH3 domain binding IEA
Inferred from Electronic Annotation
more info
  
enables actin binding IEA
Inferred from Electronic Annotation
more info
  
enables profilin binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within actin polymerization or depolymerization IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within positive regulation of actin filament polymerization IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein homotetramerization IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in stress fiber IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Enah/Vasp-like S homeolog; enah/Vasp-like S homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001096995.1 → NP_001090464.1  Enah/Vasp-like S homeolog

    See identical proteins and their annotated locations for NP_001090464.1

    Status: PROVISIONAL

    Source sequence(s)
    BC084218
    UniProtKB/TrEMBL
    Q5XH55
    Related
    ENSXLAP00005014312.1, ENSXLAT00005014508.1
    Conserved Domains (2) summary
    cd01207
    Location:5 → 113
    EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
    pfam08776
    Location:381 → 415
    VASP_tetra; VASP tetramerization domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054386.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    12487861..12581250 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018232167.2 → XP_018087656.1  enah/Vasp-like S homeolog isoform X2

    UniProtKB/TrEMBL
    A0A8J0TNS0, A0A974C1V0
    Related
    ENSXLAP00005014311.1, ENSXLAT00005014507.1

  2. XM_041574351.1 → XP_041430285.1  enah/Vasp-like S homeolog isoform X3

    UniProtKB/TrEMBL
    A0A8J1LNM3, A0A974C1V0
    Related
    ENSXLAP00005014271.1, ENSXLAT00005014467.1
    Conserved Domains (1) summary
    cd01207
    Location:7 → 115
    EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain

  3. XM_041574350.1 → XP_041430284.1  enah/Vasp-like S homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J1LMB8, A0A974C1V0
    Related
    ENSXLAP00005014266.1, ENSXLAT00005014462.1
    Conserved Domains (2) summary
    PHA03247
    Location:181 → 473
    PHA03247; large tegument protein UL36; Provisional
    cd01207
    Location:7 → 115
    EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain

  4. XM_041574353.1 → XP_041430287.1  enah/Vasp-like S homeolog isoform X5

    UniProtKB/TrEMBL
    A0A8J1LLA0
    Related
    ENSXLAP00005014278.1, ENSXLAT00005014474.1
    Conserved Domains (1) summary
    cd01207
    Location:7 → 115
    EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain

  5. XM_041574352.1 → XP_041430286.1  enah/Vasp-like S homeolog isoform X4

    UniProtKB/TrEMBL
    A0A8J1LM39
    Related
    ENSXLAP00005014313.1, ENSXLAT00005014509.1
    Conserved Domains (1) summary
    cd01207
    Location:7 → 115
    EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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