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tbxas1.L thromboxane A synthase 1 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 779365, updated on 4-Nov-2024

Summary

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Official Symbol
tbxas1.L
Official Full Name
thromboxane A synthase 1 L homeolog
Primary source
Xenbase:XB-GENE-994328
Locus tag
XELAEV_18002508mg
See related
EnsemblRapid:ENSXLAG00005006566 AllianceGenome:Xenbase:XB-GENE-994328
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
txs; cyp5; thas; txas; cyp5a1; ghosal; tbxas1
Summary
Predicted to enable several functions, including heme binding activity; iron ion binding activity; and steroid hydroxylase activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in Ghosal hematodiaphyseal syndrome and cerebral infarction. Orthologous to human TBXAS1 (thromboxane A synthase 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See tbxas1.L in Genome Data Viewer
Location:
chromosome: 3L
Exon count:
15
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3L NC_054375.1 (7022913..7051327)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) Unplaced Scaffold NW_016694822.1 (2095164..2122689)

Chromosome 3L - NC_054375.1Genomic Context describing neighboring genes Neighboring gene KIAA1549 L homeolog Neighboring gene homeodomain interacting protein kinase 2 L homeolog Neighboring gene uncharacterized LOC108704350 Neighboring gene sperm-specific basic nuclear protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC68549

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
  
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables monooxygenase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
Inferred from Electronic Annotation
more info
  
enables steroid hydroxylase activity IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
thromboxane A synthase 1, platelet
Names
thromboxane A synthase 1 (platelet)
NP_001090452.1
XP_041441225.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001096983.1 → NP_001090452.1  thromboxane A synthase 1, platelet

    See identical proteins and their annotated locations for NP_001090452.1

    Status: PROVISIONAL

    Source sequence(s)
    BC060001
    UniProtKB/TrEMBL
    Q6PAY3, Q6PCI4
    Related
    ENSXLAP00005019504.1, ENSXLAT00005019839.1
    Conserved Domains (1) summary
    pfam00067
    Location:45 → 532
    p450; Cytochrome P450

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054375.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    7022913..7051327
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041585291.1 → XP_041441225.1  thromboxane A synthase 1, platelet isoform X1

    UniProtKB/TrEMBL
    A0A8J1MJL3, Q6PCI4
    Conserved Domains (1) summary
    COG2124
    Location:84 → 535
    CypX; Cytochrome P450 [Secondary metabolites biosynthesis, transport and catabolism, Defense mechanisms]
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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