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rnf31.S ring finger protein 31 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 779341, updated on 4-Nov-2024

Summary

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Official Symbol
rnf31.S
Official Full Name
ring finger protein 31 S homeolog
Primary source
Xenbase:XB-GENE-968737
Locus tag
XELAEV_18010214mg
See related
EnsemblRapid:ENSXLAG00005012797 AllianceGenome:Xenbase:XB-GENE-968737
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
rnf31
Summary
Predicted to enable several functions, including linear polyubiquitin binding activity; polyubiquitin modification-dependent protein binding activity; and zinc ion binding activity. Predicted to act upstream of or within protein linear polyubiquitination. Predicted to be part of LUBAC complex. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human RNF31 (ring finger protein 31). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See rnf31.S in Genome Data Viewer
Location:
chromosome: 1S
Exon count:
24
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 1S NC_054372.1 (129602791..129637269, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 1S NC_030725.1 (114643728..114678642, complement)

Chromosome 1S - NC_054372.1Genomic Context describing neighboring genes Neighboring gene uncharacterized XB22041731 S homeolog Neighboring gene interferon regulatory factor 9 S homeolog Neighboring gene proteasome activator complex subunit 2 Neighboring gene proteasome activator subunit 1 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. Kırlı K, et al. Elife, 2015 Dec 17. PMID 26673895, Free PMC Article
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Clone Names

  • MGC154712

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables K48-linked polyubiquitin modification-dependent protein binding IEA
Inferred from Electronic Annotation
more info
  
enables K63-linked polyubiquitin modification-dependent protein binding IEA
Inferred from Electronic Annotation
more info
  
enables linear polyubiquitin binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
  
enables ubiquitin-protein transferase activity IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within protein linear polyubiquitination IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of LUBAC complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ring finger protein 31 S homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001096960.1 → NP_001090429.1  ring finger protein 31 S homeolog

    See identical proteins and their annotated locations for NP_001090429.1

    Status: PROVISIONAL

    Source sequence(s)
    BC126008
    UniProtKB/TrEMBL
    A0A974DVV2, A0JMU3
    Related
    ENSXLAP00005037651.1, ENSXLAT00005038562.1
    Conserved Domains (6) summary
    cd10464
    Location:42 → 150
    PUB_RNF31; PNGase/UBA or UBX (PUB) domain of the RNF31 (or HOIP) protein
    smart00647
    Location:753 → 813
    IBR; In Between Ring fingers
    sd00029
    Location:268 → 287
    zf-RanBP2; RanBP2-type Zn finger [structural motif]
    pfam01485
    Location:826 → 879
    IBR; IBR domain, a half RING-finger domain
    pfam16678
    Location:455 → 600
    HOIP-UBA; UB-associated-like domain of HOIP or E3 ubiquitin-protein ligase
    cl21463
    Location:545 → 598
    UBA_like_SF; UBA domain-like superfamily

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054372.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    129602791..129637269 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018240101.2 → XP_018095590.1  ring finger protein 31 S homeolog isoform X4

    UniProtKB/TrEMBL
    A0A8J0U2Q5, A0A974DVV2

  2. XM_018240084.2 → XP_018095573.1  ring finger protein 31 S homeolog isoform X2

    UniProtKB/TrEMBL
    A0A8J0U2P5, A0A974DVV2

  3. XM_018240092.2 → XP_018095581.1  ring finger protein 31 S homeolog isoform X3

    UniProtKB/TrEMBL
    A0A8J0U5Z4, A0A974DVV2
    Related
    ENSXLAP00005037664.1, ENSXLAT00005038575.1

  4. XM_018240075.2 → XP_018095564.1  ring finger protein 31 S homeolog isoform X1

    UniProtKB/TrEMBL
    A0A1L8HPJ6, A0A974DVV2, A0A974I1M1
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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