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anapc5.L anaphase promoting complex subunit 5 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 779325, updated on 4-Nov-2024

Summary

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Official Symbol
anapc5.L
Official Full Name
anaphase promoting complex subunit 5 L homeolog
Primary source
Xenbase:XB-GENE-978477
Locus tag
XELAEV_18007829mg
See related
AllianceGenome:Xenbase:XB-GENE-978477
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
anapc5
Summary
Predicted to act upstream of or within several processes, including anaphase-promoting complex-dependent catabolic process; positive regulation of mitotic metaphase/anaphase transition; and protein K11-linked ubiquitination. Predicted to be located in cytoplasm; nucleus; and spindle. Predicted to be part of anaphase-promoting complex. Orthologous to human ANAPC5 (anaphase promoting complex subunit 5). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See anapc5.L in Genome Data Viewer
Location:
chromosome: 1L
Exon count:
7
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 1L NC_054371.1 (176236816..176241696)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 1L NC_030724.1 (163081590..163086470)

Chromosome 1L - NC_054371.1Genomic Context describing neighboring genes Neighboring gene traf2 and NCK-interacting protein kinase-like Neighboring gene ring finger protein 34, E3 ubiquitin protein ligase L homeolog Neighboring gene calcium/calmodulin-dependent protein kinase kinase 2, beta L homeolog Neighboring gene purinergic receptor P2X, ligand gated ion channel, 4 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C. Dube P, et al. Mol Cell, 2005 Dec 22. PMID 16364912
  2. A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. Kırlı K, et al. Elife, 2015 Dec 17. PMID 26673895, Free PMC Article
  3. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Clone Names

  • MGC154883

Gene Ontology Provided by Xenbase

Process Evidence Code Pubs
acts_upstream_of_or_within anaphase-promoting complex-dependent catabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within cell division IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within positive regulation of mitotic metaphase/anaphase transition IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein K11-linked ubiquitination IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of anaphase-promoting complex IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in spindle IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
anaphase promoting complex subunit 5 L homeolog
Names
anaphase-promoting complex subunit 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001096944.1 → NP_001090413.1  anaphase promoting complex subunit 5 L homeolog

    See identical proteins and their annotated locations for NP_001090413.1

    Status: PROVISIONAL

    Source sequence(s)
    BC123367
    UniProtKB/TrEMBL
    Q0IH16
    Conserved Domains (3) summary
    sd00016
    Location:251 → 285
    Apc5; TPR repeat [structural motif]
    cd16270
    Location:32 → 162
    Apc5_N; N-terminal domain of the anaphase-promoting complex subunit Apc5 (or Anapc5)
    cl20473
    Location:257 → 319
    ANAPC5; Anaphase-promoting complex subunit 5

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054371.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    176236816..176241696
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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