nppa.S natriuretic peptide A S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: nppa.S
Official Full Name: natriuretic peptide A S homeolog
Primary source: Xenbase:XB-GENE-17342241
Locus tag: XELAEV_18037296mg
See related: EnsemblRapid:ENSXLAG00005005500 AllianceGenome:Xenbase:XB-GENE-17342241
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: anf; anp; nppa
Summary: Predicted to enable hormone activity and hormone receptor binding activity. Predicted to act upstream of or within several processes, including cGMP biosynthetic process; cGMP-mediated signaling; and receptor guanylyl cyclase signaling pathway. Predicted to be located in cytoplasm and extracellular space. Human ortholog(s) of this gene implicated in artery disease (multiple); heart conduction disease (multiple); and peritonitis. Orthologous to human NPPA (natriuretic peptide A). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information: Annotation category: partial on reference assembly
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 7S

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	7S	NC_054384.1 (53794335..53799886, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	7S	NC_030737.1 (43984161..43989712)

Chromosome 7S - NC_054384.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables hormone activity	IEA Inferred from Electronic Annotation more info
enables hormone receptor binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cGMP biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within cGMP-mediated signaling	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within negative regulation of systemic arterial blood pressure	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within neuropeptide signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within receptor guanylyl cyclase signaling pathway	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in extracellular region	IEA Inferred from Electronic Annotation more info
located_in extracellular space	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: natriuretic peptide A S homeolog

Names: natriuretic peptide precursor A

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001096918.1 → NP_001090387.1 natriuretic peptide A S homeolog precursor

See identical proteins and their annotated locations for NP_001090387.1

Status: PROVISIONAL

Source sequence(s)

BC123316

UniProtKB/TrEMBL

Q0IH46

Related

ENSXLAP00005016232.1, ENSXLAT00005016523.1

Conserved Domains (1) summary

pfam00212
Location:114 → 142

ANP; Atrial natriuretic peptide

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054384.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

53794335..53799886 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)