ctu1.L cytosolic thiouridylase subunit 1 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: ctu1.L
Official Full Name: cytosolic thiouridylase subunit 1 L homeolog
Primary source: Xenbase:XB-GENE-5872246
Locus tag: XELAEV_18006010mg
See related: EnsemblRapid:ENSXLAG00005022476 AllianceGenome:Xenbase:XB-GENE-5872246
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: ctu1; ncs6; atpbd3; comp59
Summary: Predicted to enable tRNA binding activity. Predicted to act upstream of or within tRNA thio-modification and tRNA wobble uridine modification. Predicted to be located in cytosol. Predicted to be part of cytosolic tRNA wobble base thiouridylase complex. Orthologous to human CTU1 (cytosolic thiouridylase subunit 1). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information: Annotation category: partial on reference assembly
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Genomic context

Location:: chromosome: 1L

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	1L	NC_054371.1 (96361183..96396457, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	1L	NC_030724.1 (85257612..85295001, complement)

Chromosome 1L - NC_054371.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables nucleotidyltransferase activity	IEA Inferred from Electronic Annotation more info
enables tRNA binding	IEA Inferred from Electronic Annotation more info
enables tRNA binding	ISS Inferred from Sequence or Structural Similarity more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within protein urmylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within tRNA processing	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within tRNA thio-modification	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within tRNA thio-modification	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within tRNA wobble position uridine thiolation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within tRNA wobble uridine modification	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within tRNA wobble uridine modification	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISS Inferred from Sequence or Structural Similarity more info
part_of cytosolic tRNA wobble base thiouridylase complex	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: cytoplasmic tRNA 2-thiolation protein 1

Names: cytosolic thiouridylase subunit 1 homolog

NP_001090363.1

EC 2.7.7.-

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001096894.1 → NP_001090363.1 cytoplasmic tRNA 2-thiolation protein 1

See identical proteins and their annotated locations for NP_001090363.1

Status: PROVISIONAL

Source sequence(s)

BC123240

UniProtKB/Swiss-Prot

Q05AW7

UniProtKB/TrEMBL

A0A974DY19

Related

ENSXLAP00005066095.1, ENSXLAT00005067618.1

Conserved Domains (3) summary

TIGR00269
Location:202 → 303

TIGR00269; TIGR00269 family protein

COG0037
Location:28 → 310

TilS; tRNA(Ile)-lysidine synthase TilS/MesJ [Translation, ribosomal structure and biogenesis]

cd01993
Location:52 → 238

Alpha_ANH_like_II; This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily ...

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054371.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

96361183..96396457 complement

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GenBank, FASTA, Sequence Viewer (Graphics)