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pou3f2.L POU class 3 homeobox 2 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 779122, updated on 4-Nov-2024

Summary

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Official Symbol
pou3f2.L
Official Full Name
POU class 3 homeobox 2 L homeolog
Primary source
Xenbase:XB-GENE-483178
Locus tag
XELAEV_18027255mg
See related
EnsemblRapid:ENSXLAG00005028199 AllianceGenome:Xenbase:XB-GENE-483178
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
pou3b; XlPOU3; pou3f2; pou3f4; pou3f2-A; pou3f2-b; pou3f2.S
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to act upstream of or within brain development and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in ectoderm; nervous system; vestibuloauditory system; and visual system. Orthologous to human POU3F2 (POU class 3 homeobox 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See pou3f2.L in Genome Data Viewer
Location:
chromosome: 5L
Exon count:
1
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 5L NC_054379.1 (86019877..86022146, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 5L NC_030732.1 (83802464..83804733, complement)

Chromosome 5L - NC_054379.1Genomic Context describing neighboring genes Neighboring gene coenzyme Q3 methyltransferase L homeolog Neighboring gene failed axon connections homolog L homeolog Neighboring gene MMS22 like, DNA repair protein L homeolog Neighboring gene kelch like family member 32 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transcription of XLPOU3, a brain-specific gene, during Xenopus laevis early embryogenesis. Baltzinger M, et al. Mech Dev, 1996 Aug. PMID 8887320
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC78934

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within brain development IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
POU domain, class 3, transcription factor 2-B
Names
POU class 3 homeobox 2 S homeolog
POU domain, class 3, transcription factor 4
transcription factor POU3-B
xlPOU3B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001096751.1 → NP_001090220.1  POU domain, class 3, transcription factor 2-B

    See identical proteins and their annotated locations for NP_001090220.1

    Status: PROVISIONAL

    Source sequence(s)
    BC072060
    UniProtKB/Swiss-Prot
    B1H1P3, B7ZR71, P31365, P70030, Q6IP58, Q8AVS5
    UniProtKB/TrEMBL
    A0A974CV61
    Related
    ENSXLAP00005083913.1, ENSXLAT00005085552.1
    Conserved Domains (2) summary
    smart00352
    Location:204 → 278
    POU; Found in Pit-Oct-Unc transcription factors
    pfam00046
    Location:299 → 352
    Homeobox; Homeobox domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054379.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    86019877..86022146 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P70030.1 GenPept UniProtKB/Swiss-Prot:P70030

Gene LinkOut

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