vps37c VPS37C subunit of ESCRT-I [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: vps37cprovided by ZNC
Official Full Name: VPS37C subunit of ESCRT-Iprovided by ZNC
Primary source: ZFIN:ZDB-GENE-061110-126
See related: Ensembl:ENSDARG00000031836 AllianceGenome:ZFIN:ZDB-GENE-061110-126
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:153996
Summary: Predicted to be involved in protein targeting to membrane; protein targeting to vacuole; and ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Predicted to act upstream of or within protein transport. Predicted to be located in late endosome membrane. Predicted to be part of ESCRT I complex. Orthologous to human VPS37C (VPS37C subunit of ESCRT-I). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	1	NC_007112.7 (44949977..44961479)
105	previous assembly	GRCz10 (GCF_000002035.5)	1	NC_007112.6 (44248674..44260176)

Chromosome 1 - NC_007112.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in protein targeting to membrane	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein targeting to vacuole	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within protein transport	IEA Inferred from Electronic Annotation more info
involved_in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of ESCRT I complex	IBA Inferred from Biological aspect of Ancestor more info
located_in endosome	IEA Inferred from Electronic Annotation more info
located_in late endosome membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: vacuolar protein sorting-associated protein 37C

Names: vacuolar protein sorting 37 homolog C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001077785.1 → NP_001071253.1 vacuolar protein sorting-associated protein 37C

See identical proteins and their annotated locations for NP_001071253.1

Status: PROVISIONAL

Source sequence(s)

BC127403

UniProtKB/TrEMBL

A0A0R4ICJ3, A0A8M1NAR1, A0JPF7

Related

ENSDARP00000067620.5, ENSDART00000067621.6

Conserved Domains (3) summary

pfam05837
Location:9 → 93

CENP-H; Centromere protein H (CENP-H)

pfam07200
Location:5 → 146

Mod_r; Modifier of rudimentary (Mod(r)) protein

pfam07777
Location:210 → 298

MFMR; G-box binding protein MFMR