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SMPD2 sphingomyelin phosphodiesterase 2 [ Gallus gallus (chicken) ]

Gene ID: 770663, updated on 17-Aug-2024

Summary

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Official Symbol
SMPD2provided by CGNC
Official Full Name
sphingomyelin phosphodiesterase 2provided by CGNC
Primary source
CGNC:632
See related
Ensembl:ENSGALG00010026854
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
ISC1; nSMase
Orthologs
human mouse all
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Genomic context

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See SMPD2 in Genome Data Viewer
Location:
chromosome: 26
Exon count:
11
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 26 NC_052557.1 (77388..80809, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 26 NC_052598.1 (46465..49883, complement)

Chromosome 26 - NC_052557.1Genomic Context describing neighboring genes Neighboring gene lymphoid-restricted membrane protein-like Neighboring gene microtubule associated monooxygenase, calponin and LIM domain containing 1 Neighboring gene TEA domain transcription factor 3 Neighboring gene tubby like protein 1 Neighboring gene FK506 binding protein 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables sphingomyelin phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sphingomyelin phosphodiesterase 2
Names
neutral sphingomyelinase
XP_001232516.1
XP_004934842.1
XP_015154246.1
XP_040508741.1
XP_040547189.1
XP_040547190.1
XP_040547192.1
XP_040547193.1
XP_046760149.1
XP_046789058.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052557.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    77388..80809 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001232515.7 → XP_001232516.1  sphingomyelin phosphodiesterase 2 isoform X2

    See identical proteins and their annotated locations for XP_001232516.1

    UniProtKB/TrEMBL
    A0A1D5PL80
    Conserved Domains (1) summary
    cl00490
    Location:14 → 275
    EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily

  2. XM_046904193.1 → XP_046760149.1  sphingomyelin phosphodiesterase 2 isoform X1

  3. XM_015298760.4 → XP_015154246.1  sphingomyelin phosphodiesterase 2 isoform X2

    UniProtKB/TrEMBL
    A0A1D5PL80
    Conserved Domains (1) summary
    cl00490
    Location:14 → 275
    EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily

  4. XM_004934785.5 → XP_004934842.1  sphingomyelin phosphodiesterase 2 isoform X2

    See identical proteins and their annotated locations for XP_004934842.1

    UniProtKB/TrEMBL
    A0A1D5PL80
    Related
    ENSGALP00010039713.1, ENSGALT00010065144.1
    Conserved Domains (1) summary
    cl00490
    Location:14 → 275
    EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily

  5. XM_040652807.2 → XP_040508741.1  sphingomyelin phosphodiesterase 2 isoform X2

    UniProtKB/TrEMBL
    A0A1D5PL80
    Conserved Domains (1) summary
    cl00490
    Location:14 → 275
    EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052598.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    46465..49883 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040691259.2 → XP_040547193.1  sphingomyelin phosphodiesterase 2 isoform X3

    Conserved Domains (1) summary
    cl00490
    Location:14 → 275
    EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily

  2. XM_040691255.2 → XP_040547189.1  sphingomyelin phosphodiesterase 2 isoform X2

    Conserved Domains (1) summary
    cl00490
    Location:14 → 275
    EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily

  3. XM_046933102.1 → XP_046789058.1  sphingomyelin phosphodiesterase 2 isoform X1

  4. XM_040691258.2 → XP_040547192.1  sphingomyelin phosphodiesterase 2 isoform X2

    Conserved Domains (1) summary
    cl00490
    Location:14 → 275
    EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily

  5. XM_040691256.2 → XP_040547190.1  sphingomyelin phosphodiesterase 2 isoform X2

    Conserved Domains (1) summary
    cl00490
    Location:14 → 275
    EEP; Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily
Nucleotide Protein Strain
Heading Accession and Version

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